Parasitemia/ParasitemiaUI/GUI.fs

   1 module ParasitemiaUI.GUI
   2
   3 open System
   4 open System.IO
   5 open System.Linq
   6 open System.Windows
   7 open System.Windows.Media
   8 open System.Windows.Markup
   9 open System.Windows.Shapes
  10 open System.Windows.Controls
  11 open System.Diagnostics
  12 open Microsoft.Win32 // For the common dialogs.
  13
  14 open Emgu.CV.WPF
  15
  16 open Logger
  17
  18 open ParasitemiaCore.Config
  19 open ParasitemiaCore.Utils
  20 open Types
  21
  22 let run (defaultConfig : Config) (fileToOpen : string option) =
  23     let app = new Application()
  24     let win = Views.MainWindow()
  25
  26     let state = State.State(defaultConfig)
  27     let mutable currentScale = 1.
  28     let mutable displayHealthy = false
  29     let warningBelowNumberOfRBC = 1000
  30
  31     // Initializations.
  32     let canvasCurrentImageColor = win.canvasCurrentImage.Background
  33     win.menuHightlightRBC.IsChecked <- displayHealthy
  34
  35     // Utils.
  36     let extractRBCPreview (img : Emgu.CV.Image<Emgu.CV.Structure.Bgr, byte>) (rbc : RBC) : Emgu.CV.Image<Emgu.CV.Structure.Bgr, byte> =
  37         let rbcWidth = rbc.size.Width
  38         let rbcHeight = rbc.size.Height
  39         let x = rbc.center.X - rbcWidth / 2. |> roundInt
  40         let y = rbc.center.Y - rbcHeight / 2. |> roundInt
  41         let w = roundInt rbcWidth
  42         let h = roundInt rbcHeight
  43         img.GetSubRect(System.Drawing.Rectangle(System.Drawing.Point((if x < 0 then 0 else x), (if y < 0 then 0 else y)),
  44                                                 System.Drawing.Size((if x + w >= img.Width then img.Width - x else w),
  45                                                                     (if y + h >= img.Height then img.Height - y else h))))
  46
  47     let setRBCFrameStyle (srcImg : SourceImage) (rbc : RBC) (frame : Views.RBCFrame) =
  48         frame.Opacity <- if displayHealthy || rbc.setManually || rbc.infected then 1. else 0.
  49         let color = if rbc.infected then srcImg.InfectedRBCColor else srcImg.HealthyRBCColor
  50         frame.manuallyAdded.Visibility <- if rbc.setManually then Visibility.Visible else Visibility.Hidden
  51         frame.manuallyAdded.Fill <- color
  52         frame.border.Stroke <- color
  53
  54     let RBCFrameFromExisting (srcImg : SourceImage) (rbc : RBC) (frame : Views.RBCFrame) : Views.RBCFrame =
  55         frame.Visibility <- Visibility.Visible
  56         frame.Height <- rbc.size.Height
  57         frame.Width <- rbc.size.Width
  58         frame.Tag <- rbc
  59         setRBCFrameStyle srcImg rbc frame
  60         frame.border.StrokeThickness <- 1.
  61         frame.txtRBCNumber.Text <- rbc.num.ToString()
  62         frame
  63
  64     let updateDocumentStatus () =
  65         win.txtDocumentStatus.Text <- if state.FilePath = "" then "<New document>" else state.FilePath
  66
  67     let statusMessageTimer = Threading.DispatcherTimer()
  68     statusMessageTimer.Tick.AddHandler(fun obj args -> statusMessageTimer.Stop(); win.txtMessageStatus.Text <- "")
  69     statusMessageTimer.Interval <- TimeSpan(0, 0, 2)
  70     let displayStatusMessage (message : string) =
  71         win.txtMessageStatus.Text <- message
  72         statusMessageTimer.Stop()
  73         statusMessageTimer.Start()
  74
  75     let highlightRBCFrame (frame : Views.RBCFrame) (highlight : bool) =
  76         let rbc = frame.Tag :?> RBC
  77         if highlight then
  78             frame.border.StrokeThickness <- 3.
  79             if not rbc.infected && not rbc.setManually && not displayHealthy then frame.Opacity <- 1.
  80         else
  81             frame.border.StrokeThickness <- 1.
  82             if not rbc.infected && not rbc.setManually && not displayHealthy then frame.Opacity <- 0.
  83
  84     let zoomToRBC (rbc : RBC) =
  85         win.scrollViewCurrentImage.ScrollToHorizontalOffset(rbc.center.X * currentScale - win.scrollViewCurrentImage.ViewportWidth / 2. + win.borderCurrentImage.BorderThickness.Left)
  86         win.scrollViewCurrentImage.ScrollToVerticalOffset(rbc.center.Y * currentScale - win.scrollViewCurrentImage.ViewportHeight / 2. + win.borderCurrentImage.BorderThickness.Top)
  87
  88
  89     let txtImageName_TextChanged =
  90         TextChangedEventHandler(fun obj args -> state.CurrentImage |> Option.iter(fun srcImg -> state.SetName srcImg win.txtImageName.Text))
  91
  92     let updateCurrentImageInformation () =
  93         win.txtImageName.TextChanged.RemoveHandler(txtImageName_TextChanged)
  94         win.txtImageInformation1.Inlines.Clear()
  95         win.txtImageInformation2.Inlines.Clear()
  96         win.txtImageName.Text <- ""
  97
  98         match state.CurrentImage with
  99         | Some srcImg ->
 100             win.gridImageInformation.Visibility <- Visibility.Visible
 101             win.txtImageName.Text <- srcImg.name
 102             win.txtImageName.TextChanged.AddHandler(txtImageName_TextChanged)
 103
 104             // The left part.
 105             let parasitemiaStr = Utils.percentText (state.ImageParasitemia srcImg)
 106             win.txtImageInformation1.Inlines.Add(Documents.Run("Parasitemia: ", FontWeight = FontWeights.Bold))
 107             win.txtImageInformation1.Inlines.Add(parasitemiaStr)
 108             win.txtImageInformation1.Inlines.Add(Documents.LineBreak())
 109
 110             win.txtImageInformation1.Inlines.Add(Documents.Run("Last analysis: ", FontWeight = FontWeights.Bold))
 111             win.txtImageInformation1.Inlines.Add(Documents.Run(if srcImg.dateLastAnalysis.Ticks = 0L then "<Never>" else srcImg.dateLastAnalysis.ToLocalTime().ToString()))
 112
 113             // The right part part.
 114             win.txtImageInformation2.Inlines.Add(Documents.Run("Added infected erythrocyte: ", FontWeight = FontWeights.Bold))
 115             win.txtImageInformation2.Inlines.Add(Documents.Run((state.ImageNbManuallyChangedRBCStr srcImg true) + " " + (state.ImageManuallyChangedRBCStr srcImg true)))
 116             win.txtImageInformation2.Inlines.Add(Documents.LineBreak())
 117             win.txtImageInformation2.Inlines.Add(Documents.Run("Removed infected erythrocyte: ", FontWeight = FontWeights.Bold))
 118             win.txtImageInformation2.Inlines.Add(Documents.Run((state.ImageNbManuallyChangedRBCStr srcImg false) + " " + (state.ImageManuallyChangedRBCStr srcImg false)))
 119
 120         | _ ->
 121             win.gridImageInformation.Visibility <- Visibility.Hidden
 122
 123     let updateGlobalParasitemia () =
 124         win.txtGlobalParasitemia.Inlines.Clear()
 125         let total, infected = state.GlobalParasitemia
 126         win.txtGlobalParasitemia.Inlines.Add(Documents.Run(Utils.percentText (total, infected), FontWeight = FontWeights.Bold))
 127         if total > 0 && total < warningBelowNumberOfRBC then
 128             win.txtGlobalParasitemia.Inlines.Add(
 129                 Documents.Run(
 130                     sprintf " Warning: the number of erythrocytes should be above %d" warningBelowNumberOfRBC,
 131                     FontWeight = FontWeights.Bold,
 132                     Foreground = Brushes.Red
 133                 )
 134             )
 135
 136     let updateViewportPreview () =
 137         for preview in win.stackPreviews.Children |> Seq.cast<Views.ImageSourcePreview> do
 138             let srcImg = preview.Tag :?> SourceImage
 139             if Some srcImg = state.CurrentImage then
 140                 preview.viewport.Visibility <- Visibility.Visible
 141
 142                 let canvasWidth = win.canvasCurrentImage.ActualWidth * currentScale
 143                 let canvasHeight = win.canvasCurrentImage.ActualHeight * currentScale
 144                 let previewWidth = (preview.ActualWidth - preview.BorderThickness.Left - preview.BorderThickness.Right)
 145                 let previewHeight = (preview.ActualHeight - preview.BorderThickness.Top - preview.BorderThickness.Bottom)
 146
 147                 let marginLeft = previewWidth * (win.scrollViewCurrentImage.HorizontalOffset - win.borderCurrentImage.BorderThickness.Left) / canvasWidth - 2.
 148                 let marginRight = previewWidth * (canvasWidth - (win.scrollViewCurrentImage.HorizontalOffset - win.borderCurrentImage.BorderThickness.Right) - win.scrollViewCurrentImage.ViewportWidth) / canvasWidth - 2.
 149                 let marginTop = previewHeight * (win.scrollViewCurrentImage.VerticalOffset - win.borderCurrentImage.BorderThickness.Top) / canvasHeight - 2.
 150                 let marginBottom = previewHeight * (canvasHeight - (win.scrollViewCurrentImage.VerticalOffset - win.borderCurrentImage.BorderThickness.Bottom) - win.scrollViewCurrentImage.ViewportHeight) / canvasHeight - 2.
 151
 152                 preview.viewport.Margin <-
 153                     Thickness(
 154                         marginLeft,
 155                         marginTop,
 156                         marginRight,
 157                         marginBottom
 158                     )
 159             else
 160                 preview.viewport.Visibility <- Visibility.Hidden
 161
 162     let rec setAsInfected (srcImg : SourceImage) (rbc : RBC) (infected : bool) =
 163         state.SetAsInfected rbc infected
 164         win.canvasCurrentImage.Children
 165         |> Seq.cast<Views.RBCFrame>
 166         |> Seq.iter (
 167             fun frame ->
 168                 if (frame.Tag :?> RBC) = rbc then
 169                     setRBCFrameStyle srcImg rbc frame
 170         )
 171         updateRBCFramesPreview ()
 172         updateCurrentImageInformation ()
 173         updateGlobalParasitemia ()
 174
 175     and RBCFrame (srcImg : SourceImage) (rbc : RBC) : Views.RBCFrame =
 176         let frame = RBCFrameFromExisting srcImg rbc (Views.RBCFrame())
 177         frame.SetValue(Panel.ZIndexProperty, Int32.MaxValue - rbc.num) // To be sure the
 178         frame.menuRBCSetAsHealthy.Click.AddHandler(fun obj args -> setAsInfected srcImg (frame.Tag :?> RBC) false)
 179         frame.menuRBCSetAsInfected.Click.AddHandler(fun obj args -> setAsInfected srcImg (frame.Tag :?> RBC) true)
 180         frame.ContextMenuOpening.AddHandler(
 181             fun obj args ->
 182                 if (frame.Tag :?> RBC).infected then
 183                     frame.menuRBCSetAsHealthy.Visibility <- Visibility.Visible
 184                     frame.menuRBCSetAsInfected.Visibility <- Visibility.Collapsed
 185                 else
 186                     frame.menuRBCSetAsHealthy.Visibility <- Visibility.Collapsed
 187                     frame.menuRBCSetAsInfected.Visibility <- Visibility.Visible
 188         )
 189         frame.ContextMenuClosing.AddHandler(fun obj args -> if not frame.IsMouseOver then highlightRBCFrame frame false )
 190         frame.MouseEnter.AddHandler(fun obj args -> highlightRBCFrame frame true)
 191         frame.MouseLeave.AddHandler(fun obj args -> if not frame.grid.ContextMenu.IsOpen then highlightRBCFrame frame false)
 192         frame
 193
 194     and updateRBCFramesPreview () =
 195         match state.CurrentImage with
 196         | Some srcImg ->
 197             let mutable currentPreview = 0
 198             for rbc in srcImg.rbcs |> List.filter (fun rbc -> displayHealthy || rbc.infected) do
 199                 let previewInfected =
 200                     if currentPreview < win.stackRBC.Children.Count then
 201                         RBCFrameFromExisting srcImg rbc (win.stackRBC.Children.[currentPreview] :?> Views.RBCFrame)
 202                     else
 203                         let f = RBCFrame srcImg rbc
 204                         f.MouseLeftButtonUp.AddHandler(fun obj args -> zoomToRBC (f.Tag :?> RBC))
 205                         win.stackRBC.Children.Add(f) |> ignore
 206                         f
 207
 208                 currentPreview <- currentPreview + 1
 209
 210                 previewInfected.Height <- win.stackRBC.ActualHeight
 211                 previewInfected.Width <- win.stackRBC.ActualHeight * rbc.size.Width / rbc.size.Height
 212                 previewInfected.border.Fill <- ImageBrush(BitmapSourceConvert.ToBitmapSource(extractRBCPreview srcImg.img rbc))
 213
 214             win.stackRBC.Children.RemoveRange(currentPreview, win.stackRBC.Children.Count - currentPreview)
 215         | _ -> ()
 216
 217         updateViewportPreview ()
 218
 219     let updateRBCFramesCurrent () =
 220         match state.CurrentImage with
 221         | Some srcImg ->
 222             let mutable currentCanvas = 0
 223             for rbc in srcImg.rbcs do
 224                 let frame =
 225                     if currentCanvas < win.canvasCurrentImage.Children.Count then
 226                         RBCFrameFromExisting srcImg rbc (win.canvasCurrentImage.Children.[currentCanvas] :?> Views.RBCFrame)
 227                     else
 228                         let f = RBCFrame srcImg rbc
 229                         f.Opacity <- 0.7
 230                         win.canvasCurrentImage.Children.Add(f) |> ignore
 231                         f
 232
 233                 currentCanvas <- currentCanvas + 1
 234
 235                 Canvas.SetLeft(frame, rbc.center.X - rbc.size.Width / 2.)
 236                 Canvas.SetTop(frame, rbc.center.Y - rbc.size.Height / 2.)
 237
 238             for i in currentCanvas .. win.canvasCurrentImage.Children.Count - 1 do
 239                 win.canvasCurrentImage.Children.[i].Visibility <- Visibility.Hidden
 240         | _ -> ()
 241
 242     let askDocumentPathToSave () : string option =
 243         let dialog = SaveFileDialog(AddExtension = true, DefaultExt = PiaZ.extension, Filter = PiaZ.filter)
 244
 245         if state.FilePath <> "" then
 246             dialog.FileName <- FileInfo(state.FilePath).Name
 247         elif state.PatientID <> "" then
 248             dialog.FileName <- state.PatientID + PiaZ.extension
 249
 250         let res = dialog.ShowDialog()
 251         if res.HasValue && res.Value then
 252             Some dialog.FileName
 253         else
 254             None
 255
 256     let saveCurrentDocument () =
 257         try
 258             if state.FilePath = "" then
 259                 match askDocumentPathToSave () with
 260                 | Some filepath ->
 261                     state.FilePath <- filepath
 262                     state.Save()
 263                 | _ -> ()
 264             else
 265                 state.Save()
 266             updateDocumentStatus ()
 267             displayStatusMessage "Document saved"
 268         with
 269         | :? IOException as ex ->
 270             Log.Error(ex.ToString())
 271             MessageBox.Show(sprintf "The document cannot be save in \"%s\"" state.FilePath, "Error saving the document", MessageBoxButton.OK, MessageBoxImage.Error) |> ignore
 272
 273     let saveCurrentDocumentAsNewFile () =
 274         match askDocumentPathToSave () with
 275         | Some filepath ->
 276             state.FilePath <- filepath
 277             saveCurrentDocument ()
 278         | _ -> ()
 279
 280     // Ask the use to save the current document if neccessary.
 281     let askSaveCurrent () =
 282         if state.AlteredSinceLastSave then
 283             match MessageBox.Show("Would you like to save the current document?", "Saving the current document", MessageBoxButton.YesNo, MessageBoxImage.Question) with
 284             | MessageBoxResult.Yes -> saveCurrentDocument ()
 285             | _ -> ()
 286
 287     let updateCurrentImage () =
 288         match state.CurrentImage with
 289         | Some srcImg ->
 290             win.imgLogos.Visibility <- Visibility.Collapsed
 291
 292             // Highlight the preview.
 293             win.stackPreviews.Children
 294             |> Seq.cast<Views.ImageSourcePreview>
 295             |> Seq.iter (fun preview -> preview.border.BorderThickness <- Thickness(if preview.Tag = (srcImg :> Object) then 3. else 0.))
 296
 297             win.canvasCurrentImage.Height <- float srcImg.img.Height
 298             win.canvasCurrentImage.Width <- float srcImg.img.Width
 299             win.canvasCurrentImage.Background <- ImageBrush(BitmapSourceConvert.ToBitmapSource(srcImg.img))
 300
 301             updateRBCFramesCurrent ()
 302             updateRBCFramesPreview ()
 303
 304         | None ->
 305             win.imgLogos.Visibility <- Visibility.Visible
 306
 307             win.stackRBC.Children.Clear()
 308             win.canvasCurrentImage.Children.Clear()
 309             win.canvasCurrentImage.Background <- canvasCurrentImageColor
 310
 311         updateCurrentImageInformation ()
 312
 313     let setCurrentImage (srcImg : SourceImage) =
 314         if state.CurrentImage.IsNone || state.CurrentImage.Value <> srcImg then
 315             state.CurrentImage <- Some srcImg
 316             updateCurrentImage ()
 317
 318     let addPreview (srcImg : SourceImage) =
 319         let imgCtrl = Views.ImageSourcePreview(Margin = Thickness(3.))
 320
 321         imgCtrl.menuRemoveImage.Click.AddHandler(fun obj args ->
 322             win.stackPreviews.Children.Remove(imgCtrl)
 323             let srcImg = imgCtrl.Tag :?> SourceImage
 324             let currentRemoved = Some srcImg = state.CurrentImage
 325             state.RemoveSourceImage srcImg
 326             if currentRemoved then
 327                 updateCurrentImage()
 328
 329             updateGlobalParasitemia()
 330
 331             // Update image numbers.
 332             win.stackPreviews.Children |> Seq.cast<Views.ImageSourcePreview> |> Seq.iter (fun imgPreview -> imgPreview.txtImageNumber.Text <- (imgPreview.Tag :?> SourceImage).num.ToString()))
 333
 334         imgCtrl.Tag <- srcImg
 335         imgCtrl.txtImageNumber.Text <- srcImg.num.ToString()
 336         let width = 200
 337         let height = srcImg.img.Height * width / srcImg.img.Width
 338         imgCtrl.imagePreview.Source <- BitmapSourceConvert.ToBitmapSource(srcImg.img.Resize(width, height, Emgu.CV.CvEnum.Inter.Cubic))
 339         win.stackPreviews.Children.Add(imgCtrl) |> ignore
 340
 341         // Zoom to a mouse position into the control 'imgCtrl'.
 342         let zoomTo (mousePos : Point) =
 343             let canvasW = win.canvasCurrentImage.ActualWidth * currentScale
 344             let canvasH = win.canvasCurrentImage.ActualHeight * currentScale
 345             let centerX = (mousePos.X - imgCtrl.BorderThickness.Left) / (imgCtrl.ActualWidth - imgCtrl.BorderThickness.Left) * canvasW
 346             let centerY = (mousePos.Y - imgCtrl.BorderThickness.Top) / (imgCtrl.ActualHeight - imgCtrl.BorderThickness.Top) * canvasH
 347             win.scrollViewCurrentImage.ScrollToHorizontalOffset(centerX - win.scrollViewCurrentImage.ViewportWidth / 2. + win.borderCurrentImage.BorderThickness.Left)
 348             win.scrollViewCurrentImage.ScrollToVerticalOffset(centerY - win.scrollViewCurrentImage.ViewportHeight / 2. + win.borderCurrentImage.BorderThickness.Top)
 349
 350         imgCtrl.MouseLeftButtonDown.AddHandler(fun obj args ->
 351             setCurrentImage (state.SourceImages |> Seq.find (fun srcImg -> (srcImg :> Object) = imgCtrl.Tag))
 352             imgCtrl.UpdateLayout()
 353             zoomTo (args.GetPosition(imgCtrl))
 354             imgCtrl.CaptureMouse() |> ignore
 355         )
 356
 357         imgCtrl.MouseMove.AddHandler(fun obj args ->
 358             if imgCtrl.IsMouseCaptured then
 359                 zoomTo (args.GetPosition(imgCtrl))
 360         )
 361
 362         imgCtrl.MouseLeftButtonUp.AddHandler(fun obj args ->
 363             if imgCtrl.IsMouseCaptured then
 364                 imgCtrl.ReleaseMouseCapture()
 365         )
 366
 367     let updatePreviews () =
 368         win.stackPreviews.Children.Clear ()
 369         for srcImg in state.SourceImages do
 370             addPreview srcImg
 371         updateCurrentImage ()
 372
 373     let updateGUI () =
 374         win.txtPatient.Text <- state.PatientID
 375         updatePreviews ()
 376         updateGlobalParasitemia ()
 377         updateDocumentStatus ()
 378
 379     let loadFile (filepath : string) =
 380         askSaveCurrent ()
 381         let previousFilePath = state.FilePath
 382         try
 383             state.FilePath <- filepath
 384             state.Load()
 385             updateGUI ()
 386         with
 387         | :? IOException as ex ->
 388             Log.Error(ex.ToString())
 389             state.FilePath <- previousFilePath
 390             MessageBox.Show(sprintf "The document cannot be loaded from \"%s\"" filepath, "Error loading the document", MessageBoxButton.OK, MessageBoxImage.Error) |> ignore
 391
 392     let askLoadFile () =
 393         let dialog = OpenFileDialog(Filter = PiaZ.filter)
 394         let res = dialog.ShowDialog()
 395         if res.HasValue && res.Value then
 396             loadFile dialog.FileName
 397
 398     let newFile () =
 399         askSaveCurrent ()
 400         state.Reset()
 401         updateGUI()
 402
 403     let exportResults () =
 404         let extension = ".txt"
 405         let dialog = SaveFileDialog(AddExtension = true, DefaultExt = extension)
 406
 407         if state.FilePath <> "" then
 408             dialog.FileName <- Path.GetFileNameWithoutExtension(state.FilePath) + extension
 409         elif state.PatientID <> "" then
 410             dialog.FileName <- state.PatientID + extension
 411
 412         let res = dialog.ShowDialog()
 413         if res.HasValue && res.Value then
 414             try
 415                 Export.exportResults state dialog.FileName
 416             with
 417             | :? IOException as ex ->
 418                 Log.Error(ex.ToString())
 419                 MessageBox.Show(sprintf "The results cannot be exported in \"%s\"" state.FilePath, "Error exporting the files", MessageBoxButton.OK, MessageBoxImage.Error) |> ignore
 420
 421     let importImage () =
 422         let dialog = OpenFileDialog(Filter = "Image Files|*.png;*.jpg;*.tif;*.tiff", Multiselect = true)
 423         let res = dialog.ShowDialog()
 424         if res.HasValue && res.Value then
 425             let noSourceImage = state.SourceImages.Count() = 0
 426
 427             for filename in dialog.FileNames do
 428                 try
 429                     let srcImg = state.AddSourceImage filename defaultConfig
 430                     addPreview srcImg
 431                 with
 432                 | _ as ex ->
 433                     Log.Error(ex.ToString())
 434                     MessageBox.Show(sprintf "Unable to read the image from \"%s\"" filename, "Error adding an image", MessageBoxButton.OK, MessageBoxImage.Error) |> ignore
 435
 436             updateGlobalParasitemia ()
 437
 438             if noSourceImage then
 439                 updateCurrentImage ()
 440
 441     win.txtPatient.TextChanged.AddHandler(fun obj args -> state.PatientID <- win.txtPatient.Text)
 442
 443     win.menuExit.Click.AddHandler(fun obj args -> win.Close())
 444     win.menuSave.Click.AddHandler(fun obj args -> saveCurrentDocument ())
 445     win.menuSaveAs.Click.AddHandler(fun obj args -> saveCurrentDocumentAsNewFile ())
 446     win.menuOpen.Click.AddHandler(fun obj args -> askLoadFile ())
 447     win.menuNew.Click.AddHandler(fun obj args -> newFile ())
 448     win.menuExportResults.Click.AddHandler(fun obj args -> exportResults ())
 449
 450     win.menuAddSourceImage.Click.AddHandler(fun obj args -> importImage ())
 451
 452     win.menuAnalysis.SubmenuOpened.AddHandler(fun obj args -> win.menuStartAnalysis.IsEnabled <- state.SourceImages.Count() > 0)
 453
 454     win.menuStartAnalysis.Click.AddHandler(fun obj args ->
 455         if Analysis.showWindow win state then
 456             updateGlobalParasitemia ()
 457             updateCurrentImage ()
 458     )
 459
 460     win.menuHightlightRBC.Click.AddHandler(fun obj args ->
 461         displayHealthy <- win.menuHightlightRBC.IsChecked
 462         updateRBCFramesPreview ()
 463         updateRBCFramesCurrent ()
 464     )
 465
 466     win.menuAbout.Click.AddHandler(fun obj args -> About.showWindow win)
 467
 468     win.Closing.AddHandler(fun obj args -> askSaveCurrent ())
 469
 470     // Zoom on the current image.
 471     let adjustCurrentImageBorders (deltaX : float) (deltaY : float) =
 472         win.borderCurrentImage.BorderThickness <-
 473             Thickness(
 474                 (win.scrollViewCurrentImage.ViewportWidth + deltaX) / 2.,
 475                 (win.scrollViewCurrentImage.ViewportHeight + deltaY) / 2.,
 476                 (win.scrollViewCurrentImage.ViewportWidth + deltaX) / 2.,
 477                 (win.scrollViewCurrentImage.ViewportHeight + deltaY) / 2.
 478             )
 479
 480     win.canvasCurrentImage.SizeChanged.AddHandler(fun obj args ->
 481         let deltaX = args.NewSize.Width - args.PreviousSize.Width
 482         let deltaY = args.NewSize.Height - args.PreviousSize.Height
 483         if deltaX > 0.5 || deltaY > 0.5 then
 484             adjustCurrentImageBorders 0.0 0.0
 485             // Center the view at the center of the image initialy.
 486             win.scrollViewCurrentImage.UpdateLayout()
 487             win.scrollViewCurrentImage.ScrollToHorizontalOffset(win.borderCurrentImage.ActualWidth / 2. - win.scrollViewCurrentImage.ViewportWidth / 2.)
 488             win.scrollViewCurrentImage.ScrollToVerticalOffset(win.borderCurrentImage.ActualHeight / 2. - win.scrollViewCurrentImage.ViewportHeight / 2.)
 489     )
 490
 491     win.scrollViewCurrentImage.SizeChanged.AddHandler(fun obj args ->
 492         let deltaX = args.NewSize.Width - args.PreviousSize.Width
 493         let deltaY = args.NewSize.Height - args.PreviousSize.Height
 494         adjustCurrentImageBorders deltaX deltaY
 495         win.scrollViewCurrentImage.ScrollToHorizontalOffset(win.scrollViewCurrentImage.HorizontalOffset + deltaX / 8.)
 496         win.scrollViewCurrentImage.ScrollToVerticalOffset(win.scrollViewCurrentImage.VerticalOffset + deltaY / 8.)
 497     )
 498
 499     let mutable maxScale = 4.
 500     let mutable minScale = 0.25
 501     let currentImageScaleTransform = ScaleTransform()
 502     win.canvasCurrentImage.LayoutTransform <- currentImageScaleTransform
 503     win.borderCurrentImage.PreviewMouseWheel.AddHandler(fun obj args ->
 504         let scaleFactor = if args.Delta > 0 then 2.0 else 0.5
 505         if scaleFactor > 1. && currentScale < maxScale || scaleFactor < 1. && currentScale > minScale then
 506             let previousScale = currentScale
 507             currentScale <-
 508                 let newScale = currentScale * scaleFactor
 509                 if newScale > maxScale then maxScale elif newScale < minScale then minScale else newScale
 510             let realScaleFactor = currentScale / previousScale
 511
 512             let centerX = win.scrollViewCurrentImage.HorizontalOffset + win.scrollViewCurrentImage.ViewportWidth / 2. - win.borderCurrentImage.BorderThickness.Left
 513             let centerY = win.scrollViewCurrentImage.VerticalOffset + win.scrollViewCurrentImage.ViewportHeight / 2. - win.borderCurrentImage.BorderThickness.Top
 514
 515             currentImageScaleTransform.ScaleX <- currentScale
 516             currentImageScaleTransform.ScaleY <- currentScale
 517
 518             win.scrollViewCurrentImage.ScrollToHorizontalOffset(centerX * realScaleFactor - win.scrollViewCurrentImage.ViewportWidth / 2. + win.borderCurrentImage.BorderThickness.Left)
 519             win.scrollViewCurrentImage.ScrollToVerticalOffset(centerY * realScaleFactor - win.scrollViewCurrentImage.ViewportHeight / 2. + win.borderCurrentImage.BorderThickness.Top)
 520
 521         args.Handled <- true
 522     )
 523
 524     // Pan on the current image.
 525     let mutable scrollStartPosition = Point(0., 0.)
 526     let mutable scrollStartOffsetX = 0.
 527     let mutable scrollStartOffsetY = 0.
 528     win.borderCurrentImage.PreviewMouseLeftButtonDown.AddHandler(fun obj args ->
 529         scrollStartPosition <- args.GetPosition(win.scrollViewCurrentImage)
 530         scrollStartOffsetX <- win.scrollViewCurrentImage.HorizontalOffset
 531         scrollStartOffsetY <- win.scrollViewCurrentImage.VerticalOffset
 532         win.borderCurrentImage.Cursor <- Input.Cursors.ScrollAll
 533         win.borderCurrentImage.CaptureMouse() |> ignore
 534         args.Handled <- true
 535     )
 536
 537     win.borderCurrentImage.PreviewMouseMove.AddHandler(fun obj args ->
 538         if win.borderCurrentImage.IsMouseCaptured then
 539             let position = args.GetPosition(win.scrollViewCurrentImage)
 540             let deltaX = scrollStartPosition.X - position.X
 541             let deltaY = scrollStartPosition.Y - position.Y
 542             win.scrollViewCurrentImage.ScrollToHorizontalOffset(deltaX + scrollStartOffsetX)
 543             win.scrollViewCurrentImage.ScrollToVerticalOffset(deltaY + scrollStartOffsetY)
 544
 545             args.Handled <- true
 546     )
 547
 548     win.borderCurrentImage.PreviewMouseLeftButtonUp.AddHandler(fun obj args ->
 549         if win.borderCurrentImage.IsMouseCaptured then
 550             win.borderCurrentImage.Cursor <- Input.Cursors.Arrow
 551             win.borderCurrentImage.ReleaseMouseCapture()
 552             args.Handled <- true
 553     )
 554
 555     // Shortcuts.
 556     // Save.
 557     win.InputBindings.Add(
 558         Input.KeyBinding(
 559             ViewModule.FunCommand((fun obj -> saveCurrentDocument ()), (fun obj -> true)),
 560             Input.KeyGesture(Input.Key.S, Input.ModifierKeys.Control)
 561         )
 562     ) |> ignore
 563
 564     // Save as.
 565     win.InputBindings.Add(
 566         Input.KeyBinding(
 567             ViewModule.FunCommand((fun obj -> saveCurrentDocumentAsNewFile ()), (fun obj -> true)),
 568             Input.KeyGesture(Input.Key.S, Input.ModifierKeys.Control ||| Input.ModifierKeys.Shift)
 569         )
 570     ) |> ignore
 571
 572     // Open.
 573     win.InputBindings.Add(
 574         Input.KeyBinding(
 575             ViewModule.FunCommand((fun obj -> askLoadFile ()), (fun obj -> true)),
 576             Input.KeyGesture(Input.Key.O, Input.ModifierKeys.Control)
 577         )
 578     ) |> ignore
 579
 580     // New file.
 581     win.InputBindings.Add(
 582         Input.KeyBinding(
 583             ViewModule.FunCommand((fun obj -> newFile ()), (fun obj -> true)),
 584             Input.KeyGesture(Input.Key.N, Input.ModifierKeys.Control)
 585         )
 586     ) |> ignore
 587
 588     // Export results.
 589     win.InputBindings.Add(
 590         Input.KeyBinding(
 591             ViewModule.FunCommand((fun obj -> exportResults ()), (fun obj -> true)),
 592             Input.KeyGesture(Input.Key.E, Input.ModifierKeys.Control)
 593         )
 594     ) |> ignore
 595
 596     // Import an image.
 597     win.InputBindings.Add(
 598         Input.KeyBinding(
 599             ViewModule.FunCommand((fun obj -> importImage ()), (fun obj -> true)),
 600             Input.KeyGesture(Input.Key.A, Input.ModifierKeys.Control)
 601         )
 602     ) |> ignore
 603
 604     // Viewport preview.
 605     win.scrollViewCurrentImage.ScrollChanged.AddHandler(fun obj args -> updateViewportPreview ())
 606
 607     updateDocumentStatus ()
 608     win.gridImageInformation.Visibility <- Visibility.Hidden
 609
 610     win.Show()
 611
 612     match fileToOpen with
 613     | Some filepath -> loadFile filepath
 614     | None -> ()
 615
 616     app.Run()