Parasitemia/ParasitemiaUI/GUI.fs

   1 module ParasitemiaUI.GUI
   2
   3 open System
   4 open System.IO
   5 open System.Linq
   6 open System.Windows
   7 open System.Windows.Media
   8 open System.Windows.Controls
   9 open Microsoft.Win32 // For the common dialogs.
  10
  11 open Logger
  12
  13 open ParasitemiaUIControls
  14 open ParasitemiaCore.Config
  15 open ParasitemiaCore.Utils
  16 open Types
  17
  18 let run (defaultConfig : Config) (fileToOpen : string option) =
  19     let app = new Application ()
  20     let win = MainWindow ()
  21     win.Title <- Constants.APPLICATION_NAME
  22
  23     let state = State.State defaultConfig
  24     let mutable currentScale = 1.
  25     let mutable displayHealthy = false
  26     let warningBelowNumberOfRBC = 1000
  27
  28     // Initializations.
  29     let canvasCurrentImageColor = win.canvasCurrentImage.Background
  30     win.menuHightlightRBC.IsChecked <- displayHealthy
  31
  32     // Utils.
  33     let extractRBCPreview (img : Emgu.CV.Image<Emgu.CV.Structure.Bgr, byte>) (rbc : RBC) : Emgu.CV.Image<Emgu.CV.Structure.Bgr, byte> =
  34         let rbcWidth = rbc.size.Width
  35         let rbcHeight = rbc.size.Height
  36         let x = rbc.center.X - rbcWidth / 2. |> roundInt
  37         let y = rbc.center.Y - rbcHeight / 2. |> roundInt
  38         let w = roundInt rbcWidth
  39         let h = roundInt rbcHeight
  40         img.GetSubRect (
  41             System.Drawing.Rectangle (
  42                 System.Drawing.Point ((if x < 0 then 0 else x), (if y < 0 then 0 else y)),
  43                 System.Drawing.Size ((if x + w >= img.Width then img.Width - x else w), (if y + h >= img.Height then img.Height - y else h))
  44             )
  45         )
  46
  47     let setRBCFrameStyle (srcImg : SourceImage) (rbc : RBC) (frame : RBCFrame) =
  48         frame.Opacity <- if displayHealthy || rbc.setManually || rbc.infected then 1. else 0.
  49         let color = if rbc.infected then srcImg.InfectedRBCColor else srcImg.HealthyRBCColor
  50         frame.manuallyAdded.Visibility <- if rbc.setManually then Visibility.Visible else Visibility.Hidden
  51         frame.manuallyAdded.Fill <- color
  52         frame.border.Stroke <- color
  53
  54     let frameStrokeThickness () =
  55         state.CurrentImage |> Option.map (fun img -> max 1. (img.AverageRBCSize / 100.)) |> Option.defaultValue 1.
  56
  57     let frameFontSize () =
  58         state.CurrentImage |> Option.map (fun img -> max 1. (img.AverageRBCSize / 6.)) |> Option.defaultValue 1.
  59
  60     let createRBCFrameFromExisting (srcImg : SourceImage) (rbc : RBC) (frame : RBCFrame) (frameThickness : float) (fontSize : float) (isTextBelow : bool) : RBCFrame =
  61         frame.Visibility <- Visibility.Visible
  62         frame.Width <- rbc.size.Width
  63         frame.Height <- rbc.size.Height
  64         frame.Tag <- rbc
  65         frame.IsTextBelow <- isTextBelow
  66         setRBCFrameStyle srcImg rbc frame
  67         frame.border.StrokeThickness <- frameThickness
  68         frame.txtRBCNumber.Text <- string rbc.num
  69         frame.txtRBCNumber.FontSize <- fontSize
  70         frame
  71
  72     let updateDocumentStatus () =
  73         win.txtDocumentStatus.Text <- if state.FilePath = "" then "<New document>" else state.FilePath
  74
  75     let statusMessageTimer = Threading.DispatcherTimer ()
  76     statusMessageTimer.Tick.AddHandler (fun obj args -> statusMessageTimer.Stop (); win.txtMessageStatus.Text <- "")
  77     statusMessageTimer.Interval <- TimeSpan (0, 0, 2)
  78
  79     // To show a use message while a short period of time.
  80     let displayStatusMessage (message : string) =
  81         win.txtMessageStatus.Text <- message
  82         statusMessageTimer.Stop ()
  83         statusMessageTimer.Start ()
  84
  85     let highlightRBC (rbc : RBC) (highlight : bool) =
  86         let highlightRBCFrame (rbcFrame : RBCFrame) (strokeThickness : float) =
  87             if highlight then
  88                 rbcFrame.border.StrokeThickness <- 2. * strokeThickness
  89                 if not rbc.infected && not rbc.setManually && not displayHealthy then rbcFrame.Opacity <- 1.
  90             else
  91                 rbcFrame.border.StrokeThickness <- strokeThickness
  92                 if not rbc.infected && not rbc.setManually && not displayHealthy then rbcFrame.Opacity <- 0.
  93
  94         for rbcFrame in win.stackRBC.Children |> Seq.cast<RBCFrame> do
  95             if (rbcFrame.Tag :?> RBC) = rbc then
  96                 highlightRBCFrame rbcFrame 1.
  97
  98         let strokeThicknessCanvas = frameStrokeThickness ()
  99
 100         for rbcFrame in win.canvasCurrentImage.Children |> Seq.cast<RBCFrame> do
 101             if (rbcFrame.Tag :?> RBC) = rbc then
 102                 highlightRBCFrame rbcFrame strokeThicknessCanvas
 103
 104     let zoomToRBC (rbc : RBC) =
 105         win.scrollViewCurrentImage.ScrollToHorizontalOffset (rbc.center.X * currentScale - win.scrollViewCurrentImage.ViewportWidth / 2. + win.borderCurrentImage.BorderThickness.Left)
 106         win.scrollViewCurrentImage.ScrollToVerticalOffset (rbc.center.Y * currentScale - win.scrollViewCurrentImage.ViewportHeight / 2. + win.borderCurrentImage.BorderThickness.Top)
 107
 108     let txtImageName_TextChanged =
 109         TextChangedEventHandler (fun obj args -> state.CurrentImage |> Option.iter (fun srcImg -> state.SetName srcImg win.txtImageName.Text))
 110
 111     let updateCurrentImageInformation () =
 112         win.txtImageName.TextChanged.RemoveHandler (txtImageName_TextChanged)
 113         win.txtImageInformation1.Inlines.Clear ()
 114         win.txtImageInformation2.Inlines.Clear ()
 115         win.txtImageName.Text <- ""
 116
 117         match state.CurrentImage with
 118         | Some srcImg ->
 119             win.gridImageInformation.Visibility <- Visibility.Visible
 120             win.txtImageName.Text <- srcImg.Name
 121             win.txtImageName.TextChanged.AddHandler txtImageName_TextChanged
 122
 123             // The left part.
 124             let parasitemiaStr = Utils.percentText srcImg.ImageParasitemia
 125             win.txtImageInformation1.Inlines.Add (Documents.Run ("Parasitemia: ", FontWeight = FontWeights.Bold))
 126             win.txtImageInformation1.Inlines.Add parasitemiaStr
 127             win.txtImageInformation1.Inlines.Add (Documents.LineBreak ())
 128
 129             win.txtImageInformation1.Inlines.Add (Documents.Run ("Last analysis: ", FontWeight = FontWeights.Bold))
 130             win.txtImageInformation1.Inlines.Add (Documents.Run (if srcImg.DateLastAnalysis.Ticks = 0L then "<Never>" else string (srcImg.DateLastAnalysis.ToLocalTime())))
 131
 132             // The right part part.
 133             win.txtImageInformation2.Inlines.Add (Documents.Run ("Added infected erythrocyte: ", FontWeight = FontWeights.Bold))
 134             win.txtImageInformation2.Inlines.Add (Documents.Run ((srcImg.ImageNbManuallyChangedRBCStr true) + " " + (srcImg.ImageManuallyChangedRBCStr true)))
 135             win.txtImageInformation2.Inlines.Add (Documents.LineBreak ())
 136             win.txtImageInformation2.Inlines.Add (Documents.Run ("Removed infected erythrocyte: ", FontWeight = FontWeights.Bold))
 137             win.txtImageInformation2.Inlines.Add (Documents.Run ((srcImg.ImageNbManuallyChangedRBCStr false) + " " + (srcImg.ImageManuallyChangedRBCStr false)))
 138
 139         | _ ->
 140             win.gridImageInformation.Visibility <- Visibility.Hidden
 141
 142     let updateGlobalParasitemia () =
 143         win.txtGlobalParasitemia.Inlines.Clear ()
 144         let total, infected = state.GlobalParasitemia
 145         win.txtGlobalParasitemia.Inlines.Add (Documents.Run (Utils.percentText (total, infected), FontWeight = FontWeights.Bold))
 146         if total > 0 && total < warningBelowNumberOfRBC then
 147             win.txtGlobalParasitemia.Inlines.Add (
 148                 Documents.Run (
 149                     sprintf " Warning: the number of erythrocytes should be above %d" warningBelowNumberOfRBC,
 150                     FontWeight = FontWeights.Bold,
 151                     Foreground = Brushes.Red
 152                 )
 153             )
 154
 155     let updateViewportPreview () =
 156         for preview in win.stackPreviews.Children |> Seq.cast<ImageSourcePreview> do
 157             let srcImg = preview.Tag :?> SourceImage
 158             if Some srcImg = state.CurrentImage then
 159                 preview.viewport.Visibility <- Visibility.Visible
 160
 161                 let canvasWidth = win.canvasCurrentImage.ActualWidth * currentScale
 162                 let canvasHeight = win.canvasCurrentImage.ActualHeight * currentScale
 163                 let previewWidth = (preview.ActualWidth - preview.BorderThickness.Left - preview.BorderThickness.Right)
 164                 let previewHeight = (preview.ActualHeight - preview.BorderThickness.Top - preview.BorderThickness.Bottom)
 165
 166                 let marginLeft = previewWidth * (win.scrollViewCurrentImage.HorizontalOffset - win.borderCurrentImage.BorderThickness.Left) / canvasWidth - 2.
 167                 let marginRight = previewWidth * (canvasWidth - (win.scrollViewCurrentImage.HorizontalOffset - win.borderCurrentImage.BorderThickness.Right) - win.scrollViewCurrentImage.ViewportWidth) / canvasWidth - 2.
 168                 let marginTop = previewHeight * (win.scrollViewCurrentImage.VerticalOffset - win.borderCurrentImage.BorderThickness.Top) / canvasHeight - 2.
 169                 let marginBottom = previewHeight * (canvasHeight - (win.scrollViewCurrentImage.VerticalOffset - win.borderCurrentImage.BorderThickness.Bottom) - win.scrollViewCurrentImage.ViewportHeight) / canvasHeight - 2.
 170
 171                 preview.viewport.Margin <-
 172                     Thickness (
 173                         marginLeft,
 174                         marginTop,
 175                         marginRight,
 176                         marginBottom
 177                     )
 178             else
 179                 preview.viewport.Visibility <- Visibility.Hidden
 180
 181     let rec setAsInfected (srcImg : SourceImage) (rbc : RBC) (infected : bool) =
 182         state.SetAsInfected rbc infected
 183         win.canvasCurrentImage.Children
 184         |> Seq.cast<RBCFrame>
 185         |> Seq.iter (
 186             fun frame ->
 187                 if (frame.Tag :?> RBC) = rbc then
 188                     setRBCFrameStyle srcImg rbc frame
 189         )
 190         updateRBCFramesPreview ()
 191         updateCurrentImageInformation ()
 192         updateGlobalParasitemia ()
 193
 194     and createRBCFrame (srcImg : SourceImage) (rbc : RBC) (frameThickness : float) (fontSize : float) (isTextBelow : bool) : RBCFrame =
 195         let frame = createRBCFrameFromExisting srcImg rbc (RBCFrame ()) frameThickness fontSize isTextBelow
 196         frame.SetValue (Panel.ZIndexProperty, Int32.MaxValue - rbc.num) // To be sure the
 197         frame.menuRBCSetAsHealthy.Click.AddHandler (fun obj args -> setAsInfected srcImg (frame.Tag :?> RBC) false)
 198         frame.menuRBCSetAsInfected.Click.AddHandler (fun obj args -> setAsInfected srcImg (frame.Tag :?> RBC) true)
 199         frame.ContextMenuOpening.AddHandler (
 200             fun obj args ->
 201                 if (frame.Tag :?> RBC).infected then
 202                     frame.menuRBCSetAsHealthy.Visibility <- Visibility.Visible
 203                     frame.menuRBCSetAsInfected.Visibility <- Visibility.Collapsed
 204                 else
 205                     frame.menuRBCSetAsHealthy.Visibility <- Visibility.Collapsed
 206                     frame.menuRBCSetAsInfected.Visibility <- Visibility.Visible
 207         )
 208         frame.ContextMenuClosing.AddHandler (fun obj args -> if not frame.IsMouseOver then highlightRBC (frame.Tag :?> RBC) false )
 209         frame.MouseEnter.AddHandler (fun obj args -> highlightRBC (frame.Tag :?> RBC) true)
 210         frame.MouseLeave.AddHandler (fun obj args -> if not frame.grid.ContextMenu.IsOpen then highlightRBC (frame.Tag :?> RBC) false)
 211         frame
 212
 213     and updateRBCFramesPreview () =
 214         match state.CurrentImage with
 215         | Some srcImg ->
 216             let mutable currentPreview = 0
 217             for rbc in srcImg.RBCs |> List.filter (fun rbc -> displayHealthy || rbc.infected) do
 218                 let previewInfected =
 219                     if currentPreview < win.stackRBC.Children.Count then
 220                         createRBCFrameFromExisting srcImg rbc (win.stackRBC.Children.[currentPreview] :?> RBCFrame) 1. 12. false
 221                     else
 222                         let f = createRBCFrame srcImg rbc 1. 12. false
 223                         f.MouseLeftButtonUp.AddHandler (fun obj args -> zoomToRBC (f.Tag :?> RBC))
 224                         win.stackRBC.Children.Add f |> ignore
 225                         f
 226
 227                 currentPreview <- currentPreview + 1
 228
 229                 previewInfected.Height <- win.stackRBC.ActualHeight
 230                 previewInfected.Width <- win.stackRBC.ActualHeight * rbc.size.Width / rbc.size.Height
 231                 previewInfected.border.Fill <- ImageBrush (BitmapSourceConvert.ToBitmapSource (extractRBCPreview srcImg.Img rbc))
 232
 233             win.stackRBC.Children.RemoveRange (currentPreview, win.stackRBC.Children.Count - currentPreview)
 234         | _ -> ()
 235
 236         updateViewportPreview ()
 237
 238     let updateRBCFramesCurrent () =
 239         match state.CurrentImage with
 240         | Some srcImg ->
 241             let mutable currentCanvas = 0
 242             let strokeThickness = frameStrokeThickness ()
 243             let fontSize = frameFontSize ()
 244             for rbc in srcImg.RBCs do
 245                 let frame =
 246                     if currentCanvas < win.canvasCurrentImage.Children.Count then
 247                         createRBCFrameFromExisting srcImg rbc (win.canvasCurrentImage.Children.[currentCanvas] :?> RBCFrame) strokeThickness fontSize true
 248                     else
 249                         let f = createRBCFrame srcImg rbc strokeThickness fontSize true
 250                         win.canvasCurrentImage.Children.Add f |> ignore
 251                         f
 252
 253                 currentCanvas <- currentCanvas + 1
 254
 255                 Canvas.SetLeft (frame, rbc.center.X - rbc.size.Width / 2.)
 256                 Canvas.SetTop (frame, rbc.center.Y - rbc.size.Height / 2.)
 257
 258             for i in currentCanvas .. win.canvasCurrentImage.Children.Count - 1 do
 259                 win.canvasCurrentImage.Children.[i].Visibility <- Visibility.Hidden
 260         | _ -> ()
 261
 262     let askDocumentPathToSave () : string option =
 263         let dialog = SaveFileDialog (AddExtension = true, DefaultExt = PiaZ.extension, Filter = PiaZ.filter)
 264
 265         if state.FilePath <> "" then
 266             dialog.FileName <- FileInfo(state.FilePath).Name
 267         elif state.PatientID <> "" then
 268             dialog.FileName <- state.PatientID + PiaZ.extension
 269
 270         let res = dialog.ShowDialog ()
 271         if res.HasValue && res.Value then
 272             Some dialog.FileName
 273         else
 274             None
 275
 276     let saveCurrentDocument () =
 277         try
 278             if state.FilePath = "" then
 279                 match askDocumentPathToSave () with
 280                 | Some filepath ->
 281                     state.FilePath <- filepath
 282                     state.Save ()
 283                 | _ -> ()
 284             else
 285                 state.Save ()
 286             updateDocumentStatus ()
 287             displayStatusMessage "Document saved"
 288         with
 289         | :? IOException as ex ->
 290             Log.Error "%O" ex
 291             MessageBox.Show (sprintf "The document cannot be save in \"%s\"" state.FilePath, "Error saving the document", MessageBoxButton.OK, MessageBoxImage.Error) |> ignore
 292
 293     let saveCurrentDocumentAsNewFile () =
 294         match askDocumentPathToSave () with
 295         | Some filepath ->
 296             state.FilePath <- filepath
 297             saveCurrentDocument ()
 298         | _ -> ()
 299
 300     // Ask the use to save the current document if neccessary.
 301     let askSaveCurrent () =
 302         if state.AlteredSinceLastSave then
 303             match MessageBox.Show ("Would you like to save the current document?", "Saving the current document", MessageBoxButton.YesNo, MessageBoxImage.Question) with
 304             | MessageBoxResult.Yes -> saveCurrentDocument ()
 305             | _ -> ()
 306
 307     let updateCurrentImage () =
 308         match state.CurrentImage with
 309         | Some srcImg ->
 310             win.imgLogos.Visibility <- Visibility.Collapsed
 311
 312             // Highlight the preview.
 313             win.stackPreviews.Children
 314             |> Seq.cast<ImageSourcePreview>
 315             |> Seq.iter (fun preview -> preview.border.BorderThickness <- Thickness (if preview.Tag = (srcImg :> Object) then 3. else 0.))
 316
 317             win.canvasCurrentImage.Height <- float srcImg.Img.Height
 318             win.canvasCurrentImage.Width <- float srcImg.Img.Width
 319             win.canvasCurrentImage.Background <- ImageBrush (BitmapSourceConvert.ToBitmapSource (srcImg.Img))
 320
 321             updateRBCFramesCurrent ()
 322             updateRBCFramesPreview ()
 323
 324         | None ->
 325             win.imgLogos.Visibility <- Visibility.Visible
 326
 327             win.stackRBC.Children.Clear ()
 328             win.canvasCurrentImage.Children.Clear ()
 329             win.canvasCurrentImage.Background <- canvasCurrentImageColor
 330
 331         updateCurrentImageInformation ()
 332
 333     let setCurrentImage (srcImg : SourceImage) =
 334         if state.CurrentImage.IsNone || state.CurrentImage.Value <> srcImg then
 335             state.CurrentImage <- Some srcImg
 336             updateCurrentImage ()
 337
 338     let addPreview (srcImg : SourceImage) =
 339         let imgCtrl = ImageSourcePreview (Margin = Thickness 3.)
 340
 341         imgCtrl.menuRemoveImage.Click.AddHandler (
 342             fun obj args ->
 343                 win.stackPreviews.Children.Remove (imgCtrl)
 344                 let srcImg = imgCtrl.Tag :?> SourceImage
 345                 let currentRemoved = Some srcImg = state.CurrentImage
 346                 state.RemoveSourceImage srcImg
 347                 if currentRemoved then
 348                     updateCurrentImage ()
 349
 350                 updateGlobalParasitemia ()
 351
 352                 // Update image numbers.
 353                 win.stackPreviews.Children |> Seq.cast<ImageSourcePreview> |> Seq.iter (fun imgPreview -> imgPreview.txtImageNumber.Text <- (imgPreview.Tag :?> SourceImage).RomanNum)
 354         )
 355
 356         imgCtrl.Tag <- srcImg
 357         imgCtrl.txtImageNumber.Text <- string srcImg.RomanNum
 358         let width = 200
 359         let height = srcImg.Img.Height * width / srcImg.Img.Width
 360         imgCtrl.imagePreview.Source <- BitmapSourceConvert.ToBitmapSource (srcImg.Img.Resize (width, height, Emgu.CV.CvEnum.Inter.Cubic))
 361         win.stackPreviews.Children.Add imgCtrl |> ignore
 362
 363         // Zoom to a mouse position into the control 'imgCtrl'.
 364         let zoomTo (mousePos : Point) =
 365             let canvasW = win.canvasCurrentImage.ActualWidth * currentScale
 366             let canvasH = win.canvasCurrentImage.ActualHeight * currentScale
 367             let centerX = (mousePos.X - imgCtrl.BorderThickness.Left) / (imgCtrl.ActualWidth - imgCtrl.BorderThickness.Left) * canvasW
 368             let centerY = (mousePos.Y - imgCtrl.BorderThickness.Top) / (imgCtrl.ActualHeight - imgCtrl.BorderThickness.Top) * canvasH
 369             win.scrollViewCurrentImage.ScrollToHorizontalOffset (centerX - win.scrollViewCurrentImage.ViewportWidth / 2. + win.borderCurrentImage.BorderThickness.Left)
 370             win.scrollViewCurrentImage.ScrollToVerticalOffset (centerY - win.scrollViewCurrentImage.ViewportHeight / 2. + win.borderCurrentImage.BorderThickness.Top)
 371
 372         imgCtrl.MouseLeftButtonDown.AddHandler (
 373             fun obj args ->
 374                 setCurrentImage (state.SourceImages |> Seq.find (fun srcImg -> (srcImg :> Object) = imgCtrl.Tag))
 375                 imgCtrl.UpdateLayout ()
 376                 zoomTo (args.GetPosition (imgCtrl))
 377                 imgCtrl.CaptureMouse () |> ignore
 378         )
 379
 380         imgCtrl.MouseMove.AddHandler (
 381             fun obj args ->
 382                 if imgCtrl.IsMouseCaptured then
 383                     zoomTo (args.GetPosition imgCtrl)
 384         )
 385
 386         imgCtrl.MouseLeftButtonUp.AddHandler (
 387             fun obj args ->
 388                 if imgCtrl.IsMouseCaptured then
 389                     imgCtrl.ReleaseMouseCapture ()
 390         )
 391
 392     let updatePreviews () =
 393         win.stackPreviews.Children.Clear ()
 394         for srcImg in state.SourceImages do
 395             addPreview srcImg
 396         updateCurrentImage ()
 397
 398     let updateGUI () =
 399         win.txtPatient.Text <- state.PatientID
 400         updatePreviews ()
 401         updateGlobalParasitemia ()
 402         updateDocumentStatus ()
 403
 404     let loadFile (filepath : string) =
 405         let displayLoadingErrorMessage (message : string) =
 406             MessageBox.Show (sprintf "The document cannot be loaded from \"%s\": %s" filepath message, "Error loading the document", MessageBoxButton.OK, MessageBoxImage.Error) |> ignore
 407
 408         askSaveCurrent ()
 409         let previousFilePath = state.FilePath
 410         try
 411             state.FilePath <- filepath
 412             state.Load ()
 413             updateGUI ()
 414         with
 415         | PiaZ.VersionFileNewerException fileVersion ->
 416             state.FilePath <- previousFilePath
 417             displayLoadingErrorMessage $"File version ({fileVersion}) is newer than supported one ({PiaZ.CURRENT_FILE_VERSION}), you may update Parasitemia to the latest version"
 418
 419         | :? IOException as ex ->
 420             Log.Error "%O" ex
 421             state.FilePath <- previousFilePath
 422             displayLoadingErrorMessage "IO Error"
 423
 424     let askLoadFile () =
 425         let dialog = OpenFileDialog (Filter = PiaZ.filter)
 426         let res = dialog.ShowDialog ()
 427         if res.HasValue && res.Value then
 428             loadFile dialog.FileName
 429
 430     let newFile () =
 431         askSaveCurrent ()
 432         state.Reset ()
 433         updateGUI ()
 434
 435     let exportResults () =
 436         let extension = ".txt"
 437         let dialog = SaveFileDialog (AddExtension = true, DefaultExt = extension)
 438
 439         if state.FilePath <> "" then
 440             dialog.FileName <- Path.GetFileNameWithoutExtension state.FilePath + extension
 441         elif state.PatientID <> "" then
 442             dialog.FileName <- state.PatientID + extension
 443
 444         let res = dialog.ShowDialog ()
 445         if res.HasValue && res.Value then
 446             try
 447                 Export.exportResults state dialog.FileName
 448             with
 449             | :? IOException as ex ->
 450                 Log.Error "%O" ex
 451                 MessageBox.Show (sprintf "The results cannot be exported in \"%s\"" state.FilePath, "Error exporting the files", MessageBoxButton.OK, MessageBoxImage.Error) |> ignore
 452
 453     let importImage () =
 454         let dialog = OpenFileDialog (Filter = "Image Files|*.png;*.jpg;.jpeg;.bmp;*.tif;*.tiff", Multiselect = true)
 455         let res = dialog.ShowDialog ()
 456         if res.HasValue && res.Value then
 457             let noSourceImage = state.SourceImages.Count () = 0
 458
 459             for filename in dialog.FileNames do
 460                 try
 461                     let srcImg = state.AddSourceImage filename defaultConfig
 462                     addPreview srcImg
 463                 with
 464                 | _ as ex ->
 465                     Log.Error "%O" ex
 466                     MessageBox.Show (sprintf "Unable to read the image from \"%s\"" filename, "Error adding an image", MessageBoxButton.OK, MessageBoxImage.Error) |> ignore
 467
 468             updateGlobalParasitemia ()
 469
 470             if noSourceImage then
 471                 updateCurrentImage ()
 472
 473     let showAnalysisWindow () =
 474         if Analysis.showWindow win state then
 475             updateGlobalParasitemia ()
 476             updateCurrentImage ()
 477
 478     let setHighlightRBC (highlight : bool) =
 479         displayHealthy <- highlight
 480         updateRBCFramesPreview ()
 481         updateRBCFramesCurrent ()
 482
 483     win.txtPatient.TextChanged.AddHandler (fun obj args -> state.PatientID <- win.txtPatient.Text)
 484
 485     win.menuExit.Click.AddHandler (fun obj args -> win.Close ())
 486     win.menuSave.Click.AddHandler (fun obj args -> saveCurrentDocument ())
 487     win.menuSaveAs.Click.AddHandler (fun obj args -> saveCurrentDocumentAsNewFile ())
 488     win.menuOpen.Click.AddHandler (fun obj args -> askLoadFile ())
 489     win.menuNew.Click.AddHandler (fun obj args -> newFile ())
 490     win.menuExportResults.Click.AddHandler (fun obj args -> exportResults ())
 491
 492     win.menuAddSourceImage.Click.AddHandler (fun obj args -> importImage ())
 493
 494     win.menuAnalysis.SubmenuOpened.AddHandler (fun obj args -> win.menuStartAnalysis.IsEnabled <- state.SourceImages.Count () > 0)
 495
 496     win.menuStartAnalysis.Click.AddHandler (fun obj args -> showAnalysisWindow ())
 497
 498     win.menuHightlightRBC.Click.AddHandler (fun obj args -> setHighlightRBC win.menuHightlightRBC.IsChecked)
 499
 500     win.menuAbout.Click.AddHandler (fun obj args -> About.showWindow win)
 501
 502     win.menuCommandLineArguments.Click.AddHandler (fun obj args -> CommandLineArguments.showWindow win)
 503
 504     win.Closing.AddHandler (fun obj args -> askSaveCurrent ())
 505
 506     // Zoom on the current image.
 507     let adjustCurrentImageBorders (deltaX : float) (deltaY : float) =
 508         win.borderCurrentImage.BorderThickness <-
 509             Thickness (
 510                 (win.scrollViewCurrentImage.ViewportWidth + deltaX) / 2.,
 511                 (win.scrollViewCurrentImage.ViewportHeight + deltaY) / 2.,
 512                 (win.scrollViewCurrentImage.ViewportWidth + deltaX) / 2.,
 513                 (win.scrollViewCurrentImage.ViewportHeight + deltaY) / 2.
 514             )
 515
 516     win.canvasCurrentImage.SizeChanged.AddHandler (
 517         fun obj args ->
 518             let deltaX = args.NewSize.Width - args.PreviousSize.Width
 519             let deltaY = args.NewSize.Height - args.PreviousSize.Height
 520             if deltaX > 0.5 || deltaY > 0.5 then
 521                 adjustCurrentImageBorders 0.0 0.0
 522                 // Center the view at the center of the image initialy.
 523                 win.scrollViewCurrentImage.UpdateLayout ()
 524                 win.scrollViewCurrentImage.ScrollToHorizontalOffset (win.borderCurrentImage.ActualWidth / 2. - win.scrollViewCurrentImage.ViewportWidth / 2.)
 525                 win.scrollViewCurrentImage.ScrollToVerticalOffset (win.borderCurrentImage.ActualHeight / 2. - win.scrollViewCurrentImage.ViewportHeight / 2.)
 526     )
 527
 528     win.scrollViewCurrentImage.SizeChanged.AddHandler (
 529         fun obj args ->
 530             let deltaX = args.NewSize.Width - args.PreviousSize.Width
 531             let deltaY = args.NewSize.Height - args.PreviousSize.Height
 532             adjustCurrentImageBorders deltaX deltaY
 533             win.scrollViewCurrentImage.ScrollToHorizontalOffset (win.scrollViewCurrentImage.HorizontalOffset + deltaX / 8.)
 534             win.scrollViewCurrentImage.ScrollToVerticalOffset (win.scrollViewCurrentImage.VerticalOffset + deltaY / 8.)
 535     )
 536
 537     let mutable maxScale = 4.
 538     let mutable minScale = 0.25
 539     let currentImageScaleTransform = ScaleTransform ()
 540     win.canvasCurrentImage.LayoutTransform <- currentImageScaleTransform
 541     win.borderCurrentImage.PreviewMouseWheel.AddHandler (
 542         fun _obj args ->
 543             let scaleFactor = if args.Delta > 0 then 2.0 else 0.5
 544             if scaleFactor > 1. && currentScale < maxScale || scaleFactor < 1. && currentScale > minScale then
 545                 let previousScale = currentScale
 546                 currentScale <-
 547                     let newScale = currentScale * scaleFactor
 548                     if newScale > maxScale then maxScale elif newScale < minScale then minScale else newScale
 549                 let realScaleFactor = currentScale / previousScale
 550
 551                 let centerX = win.scrollViewCurrentImage.HorizontalOffset + win.scrollViewCurrentImage.ViewportWidth / 2. - win.borderCurrentImage.BorderThickness.Left
 552                 let centerY = win.scrollViewCurrentImage.VerticalOffset + win.scrollViewCurrentImage.ViewportHeight / 2. - win.borderCurrentImage.BorderThickness.Top
 553
 554                 currentImageScaleTransform.ScaleX <- currentScale
 555                 currentImageScaleTransform.ScaleY <- currentScale
 556
 557                 win.scrollViewCurrentImage.ScrollToHorizontalOffset (centerX * realScaleFactor - win.scrollViewCurrentImage.ViewportWidth / 2. + win.borderCurrentImage.BorderThickness.Left)
 558                 win.scrollViewCurrentImage.ScrollToVerticalOffset (centerY * realScaleFactor - win.scrollViewCurrentImage.ViewportHeight / 2. + win.borderCurrentImage.BorderThickness.Top)
 559
 560             args.Handled <- true
 561     )
 562
 563     // Pan on the current image.
 564     let mutable scrollStartPosition = Point (0., 0.)
 565     let mutable scrollStartOffsetX = 0.
 566     let mutable scrollStartOffsetY = 0.
 567     win.borderCurrentImage.PreviewMouseLeftButtonDown.AddHandler (
 568         fun _obj args ->
 569             scrollStartPosition <- args.GetPosition win.scrollViewCurrentImage
 570             scrollStartOffsetX <- win.scrollViewCurrentImage.HorizontalOffset
 571             scrollStartOffsetY <- win.scrollViewCurrentImage.VerticalOffset
 572             win.borderCurrentImage.Cursor <- Input.Cursors.ScrollAll
 573             win.borderCurrentImage.CaptureMouse () |> ignore
 574             args.Handled <- true
 575     )
 576
 577     win.borderCurrentImage.PreviewMouseMove.AddHandler (
 578         fun _obj args ->
 579             if win.borderCurrentImage.IsMouseCaptured then
 580                 let position = args.GetPosition win.scrollViewCurrentImage
 581                 let deltaX = scrollStartPosition.X - position.X
 582                 let deltaY = scrollStartPosition.Y - position.Y
 583                 win.scrollViewCurrentImage.ScrollToHorizontalOffset (deltaX + scrollStartOffsetX)
 584                 win.scrollViewCurrentImage.ScrollToVerticalOffset (deltaY + scrollStartOffsetY)
 585
 586                 args.Handled <- true
 587     )
 588
 589     win.borderCurrentImage.PreviewMouseLeftButtonUp.AddHandler (
 590         fun _obj args ->
 591             if win.borderCurrentImage.IsMouseCaptured then
 592                 win.borderCurrentImage.Cursor <- Input.Cursors.Arrow
 593                 win.borderCurrentImage.ReleaseMouseCapture ()
 594                 args.Handled <- true
 595     )
 596
 597     // Shortcuts.
 598     // Save.
 599     win.InputBindings.Add (
 600         Input.KeyBinding (
 601             Utils.FunCommand ((fun obj -> saveCurrentDocument ()), (fun obj -> true)),
 602             Input.KeyGesture (Input.Key.S, Input.ModifierKeys.Control)
 603         )
 604     ) |> ignore
 605
 606     // Save as.
 607     win.InputBindings.Add (
 608         Input.KeyBinding (
 609             Utils.FunCommand ((fun obj -> saveCurrentDocumentAsNewFile ()), (fun obj -> true)),
 610             Input.KeyGesture (Input.Key.S, Input.ModifierKeys.Control ||| Input.ModifierKeys.Shift)
 611         )
 612     ) |> ignore
 613
 614     // Open.
 615     win.InputBindings.Add (
 616         Input.KeyBinding (
 617             Utils.FunCommand ((fun obj -> askLoadFile ()), (fun obj -> true)),
 618             Input.KeyGesture (Input.Key.O, Input.ModifierKeys.Control)
 619         )
 620     ) |> ignore
 621
 622     // New file.
 623     win.InputBindings.Add (
 624         Input.KeyBinding (
 625             Utils.FunCommand ((fun obj -> newFile ()), (fun obj -> true)),
 626             Input.KeyGesture (Input.Key.N, Input.ModifierKeys.Control)
 627         )
 628     ) |> ignore
 629
 630     // Export results.
 631     win.InputBindings.Add (
 632         Input.KeyBinding (
 633             Utils.FunCommand ((fun obj -> exportResults ()), (fun obj -> true)),
 634             Input.KeyGesture (Input.Key.E, Input.ModifierKeys.Control)
 635         )
 636     ) |> ignore
 637
 638     // Import an image.
 639     win.InputBindings.Add (
 640         Input.KeyBinding (
 641             Utils.FunCommand ((fun obj -> importImage ()), (fun obj -> true)),
 642             Input.KeyGesture (Input.Key.A, Input.ModifierKeys.Control)
 643         )
 644     ) |> ignore
 645
 646     // Show analysis dialog.
 647     win.InputBindings.Add (
 648         Input.KeyBinding (
 649             Utils.FunCommand ((fun obj -> showAnalysisWindow ()), (fun obj -> state.SourceImages.Count () > 0)),
 650             Input.KeyGesture (Input.Key.Y, Input.ModifierKeys.Control)
 651         )
 652     ) |> ignore
 653
 654     // Toggle RBC highlight.
 655     win.InputBindings.Add (
 656         Input.KeyBinding (
 657             Utils.FunCommand (
 658                 (
 659                     fun obj ->
 660                         win.menuHightlightRBC.IsChecked <- not win.menuHightlightRBC.IsChecked
 661                         setHighlightRBC win.menuHightlightRBC.IsChecked
 662                 ),
 663                 (fun obj -> true)
 664             ),
 665             Input.KeyGesture (Input.Key.H, Input.ModifierKeys.Control)
 666         )
 667     ) |> ignore
 668
 669     // Viewport preview.
 670     win.scrollViewCurrentImage.ScrollChanged.AddHandler (fun obj args -> updateViewportPreview ())
 671
 672     updateDocumentStatus ()
 673     win.gridImageInformation.Visibility <- Visibility.Hidden
 674
 675     win.Show ()
 676
 677     match fileToOpen with
 678     | Some filepath -> loadFile filepath
 679     | None -> ()
 680
 681     app.Run ()