Parasitemia/ParasitemiaUI/GUI.fs

   1 module ParasitemiaUI.GUI
   2
   3 open System
   4 open System.IO
   5 open System.Linq
   6 open System.Windows
   7 open System.Windows.Media
   8 open System.Windows.Controls
   9 open Microsoft.Win32 // For the common dialogs.
  10
  11 open Logger
  12
  13 open ParasitemiaUIControls
  14 open ParasitemiaCore.Config
  15 open ParasitemiaCore.Utils
  16 open Types
  17
  18 let run (defaultConfig : Config) (fileToOpen : string option) =
  19     let app = new Application ()
  20     let win = MainWindow ()
  21
  22     let state = State.State defaultConfig
  23     let mutable currentScale = 1.
  24     let mutable displayHealthy = false
  25     let warningBelowNumberOfRBC = 1000
  26
  27     // Initializations.
  28     let canvasCurrentImageColor = win.canvasCurrentImage.Background
  29     win.menuHightlightRBC.IsChecked <- displayHealthy
  30
  31     // Utils.
  32     let extractRBCPreview (img : Emgu.CV.Image<Emgu.CV.Structure.Bgr, byte>) (rbc : RBC) : Emgu.CV.Image<Emgu.CV.Structure.Bgr, byte> =
  33         let rbcWidth = rbc.size.Width
  34         let rbcHeight = rbc.size.Height
  35         let x = rbc.center.X - rbcWidth / 2. |> roundInt
  36         let y = rbc.center.Y - rbcHeight / 2. |> roundInt
  37         let w = roundInt rbcWidth
  38         let h = roundInt rbcHeight
  39         img.GetSubRect (
  40             System.Drawing.Rectangle (
  41                 System.Drawing.Point ((if x < 0 then 0 else x), (if y < 0 then 0 else y)),
  42                 System.Drawing.Size ((if x + w >= img.Width then img.Width - x else w), (if y + h >= img.Height then img.Height - y else h))
  43             )
  44         )
  45
  46     let setRBCFrameStyle (srcImg : SourceImage) (rbc : RBC) (frame : RBCFrame) =
  47         frame.Opacity <- if displayHealthy || rbc.setManually || rbc.infected then 1. else 0.
  48         let color = if rbc.infected then srcImg.InfectedRBCColor else srcImg.HealthyRBCColor
  49         frame.manuallyAdded.Visibility <- if rbc.setManually then Visibility.Visible else Visibility.Hidden
  50         frame.manuallyAdded.Fill <- color
  51         frame.border.Stroke <- color
  52
  53     let frameStrokeThickness (averageRBCSize : float) =
  54         max 1. (averageRBCSize / 60.)
  55
  56     let frameFontSize (averageRBCSize : float) =
  57         max 1. (averageRBCSize / 6.)
  58
  59     let createRBCFrameFromExisting (srcImg : SourceImage) (rbc : RBC) (frame : RBCFrame) (frameThickness : float) (fontSize : float) (isTextBelow : bool) : RBCFrame =
  60         frame.Visibility <- Visibility.Visible
  61         frame.Width <- rbc.size.Width
  62         frame.Height <- rbc.size.Height
  63         frame.Tag <- rbc
  64         frame.IsTextBelow <- isTextBelow
  65         setRBCFrameStyle srcImg rbc frame
  66         frame.border.StrokeThickness <- frameThickness
  67         frame.txtRBCNumber.Text <- string rbc.num
  68         frame.txtRBCNumber.FontSize <- fontSize
  69         frame
  70
  71     let updateDocumentStatus () =
  72         win.txtDocumentStatus.Text <- if state.FilePath = "" then "<New document>" else state.FilePath
  73
  74     let statusMessageTimer = Threading.DispatcherTimer ()
  75     statusMessageTimer.Tick.AddHandler (fun obj args -> statusMessageTimer.Stop (); win.txtMessageStatus.Text <- "")
  76     statusMessageTimer.Interval <- TimeSpan (0, 0, 2)
  77
  78     // To show a use message while a short period of time.
  79     let displayStatusMessage (message : string) =
  80         win.txtMessageStatus.Text <- message
  81         statusMessageTimer.Stop ()
  82         statusMessageTimer.Start ()
  83
  84     let highlightRBCFrame (frame : RBCFrame) (highlight : bool) =
  85         let rbc = frame.Tag :?> RBC
  86         if highlight then
  87             frame.border.StrokeThickness <- 3. * frame.border.StrokeThickness
  88             if not rbc.infected && not rbc.setManually && not displayHealthy then frame.Opacity <- 1.
  89         else
  90             frame.border.StrokeThickness <- frame.border.StrokeThickness / 3.
  91             if not rbc.infected && not rbc.setManually && not displayHealthy then frame.Opacity <- 0.
  92
  93     let zoomToRBC (rbc : RBC) =
  94         win.scrollViewCurrentImage.ScrollToHorizontalOffset (rbc.center.X * currentScale - win.scrollViewCurrentImage.ViewportWidth / 2. + win.borderCurrentImage.BorderThickness.Left)
  95         win.scrollViewCurrentImage.ScrollToVerticalOffset (rbc.center.Y * currentScale - win.scrollViewCurrentImage.ViewportHeight / 2. + win.borderCurrentImage.BorderThickness.Top)
  96
  97     let txtImageName_TextChanged =
  98         TextChangedEventHandler (fun obj args -> state.CurrentImage |> Option.iter (fun srcImg -> state.SetName srcImg win.txtImageName.Text))
  99
 100     let updateCurrentImageInformation () =
 101         win.txtImageName.TextChanged.RemoveHandler (txtImageName_TextChanged)
 102         win.txtImageInformation1.Inlines.Clear ()
 103         win.txtImageInformation2.Inlines.Clear ()
 104         win.txtImageName.Text <- ""
 105
 106         match state.CurrentImage with
 107         | Some srcImg ->
 108             win.gridImageInformation.Visibility <- Visibility.Visible
 109             win.txtImageName.Text <- srcImg.Name
 110             win.txtImageName.TextChanged.AddHandler txtImageName_TextChanged
 111
 112             // The left part.
 113             let parasitemiaStr = Utils.percentText srcImg.ImageParasitemia
 114             win.txtImageInformation1.Inlines.Add (Documents.Run ("Parasitemia: ", FontWeight = FontWeights.Bold))
 115             win.txtImageInformation1.Inlines.Add parasitemiaStr
 116             win.txtImageInformation1.Inlines.Add (Documents.LineBreak ())
 117
 118             win.txtImageInformation1.Inlines.Add (Documents.Run ("Last analysis: ", FontWeight = FontWeights.Bold))
 119             win.txtImageInformation1.Inlines.Add (Documents.Run (if srcImg.DateLastAnalysis.Ticks = 0L then "<Never>" else string (srcImg.DateLastAnalysis.ToLocalTime())))
 120
 121             // The right part part.
 122             win.txtImageInformation2.Inlines.Add (Documents.Run ("Added infected erythrocyte: ", FontWeight = FontWeights.Bold))
 123             win.txtImageInformation2.Inlines.Add (Documents.Run ((srcImg.ImageNbManuallyChangedRBCStr true) + " " + (srcImg.ImageManuallyChangedRBCStr true)))
 124             win.txtImageInformation2.Inlines.Add (Documents.LineBreak ())
 125             win.txtImageInformation2.Inlines.Add (Documents.Run ("Removed infected erythrocyte: ", FontWeight = FontWeights.Bold))
 126             win.txtImageInformation2.Inlines.Add (Documents.Run ((srcImg.ImageNbManuallyChangedRBCStr false) + " " + (srcImg.ImageManuallyChangedRBCStr false)))
 127
 128         | _ ->
 129             win.gridImageInformation.Visibility <- Visibility.Hidden
 130
 131     let updateGlobalParasitemia () =
 132         win.txtGlobalParasitemia.Inlines.Clear ()
 133         let total, infected = state.GlobalParasitemia
 134         win.txtGlobalParasitemia.Inlines.Add (Documents.Run (Utils.percentText (total, infected), FontWeight = FontWeights.Bold))
 135         if total > 0 && total < warningBelowNumberOfRBC then
 136             win.txtGlobalParasitemia.Inlines.Add (
 137                 Documents.Run (
 138                     sprintf " Warning: the number of erythrocytes should be above %d" warningBelowNumberOfRBC,
 139                     FontWeight = FontWeights.Bold,
 140                     Foreground = Brushes.Red
 141                 )
 142             )
 143
 144     let updateViewportPreview () =
 145         for preview in win.stackPreviews.Children |> Seq.cast<ImageSourcePreview> do
 146             let srcImg = preview.Tag :?> SourceImage
 147             if Some srcImg = state.CurrentImage then
 148                 preview.viewport.Visibility <- Visibility.Visible
 149
 150                 let canvasWidth = win.canvasCurrentImage.ActualWidth * currentScale
 151                 let canvasHeight = win.canvasCurrentImage.ActualHeight * currentScale
 152                 let previewWidth = (preview.ActualWidth - preview.BorderThickness.Left - preview.BorderThickness.Right)
 153                 let previewHeight = (preview.ActualHeight - preview.BorderThickness.Top - preview.BorderThickness.Bottom)
 154
 155                 let marginLeft = previewWidth * (win.scrollViewCurrentImage.HorizontalOffset - win.borderCurrentImage.BorderThickness.Left) / canvasWidth - 2.
 156                 let marginRight = previewWidth * (canvasWidth - (win.scrollViewCurrentImage.HorizontalOffset - win.borderCurrentImage.BorderThickness.Right) - win.scrollViewCurrentImage.ViewportWidth) / canvasWidth - 2.
 157                 let marginTop = previewHeight * (win.scrollViewCurrentImage.VerticalOffset - win.borderCurrentImage.BorderThickness.Top) / canvasHeight - 2.
 158                 let marginBottom = previewHeight * (canvasHeight - (win.scrollViewCurrentImage.VerticalOffset - win.borderCurrentImage.BorderThickness.Bottom) - win.scrollViewCurrentImage.ViewportHeight) / canvasHeight - 2.
 159
 160                 preview.viewport.Margin <-
 161                     Thickness (
 162                         marginLeft,
 163                         marginTop,
 164                         marginRight,
 165                         marginBottom
 166                     )
 167             else
 168                 preview.viewport.Visibility <- Visibility.Hidden
 169
 170     let rec setAsInfected (srcImg : SourceImage) (rbc : RBC) (infected : bool) =
 171         state.SetAsInfected rbc infected
 172         win.canvasCurrentImage.Children
 173         |> Seq.cast<RBCFrame>
 174         |> Seq.iter (
 175             fun frame ->
 176                 if (frame.Tag :?> RBC) = rbc then
 177                     setRBCFrameStyle srcImg rbc frame
 178         )
 179         updateRBCFramesPreview ()
 180         updateCurrentImageInformation ()
 181         updateGlobalParasitemia ()
 182
 183     and createRBCFrame (srcImg : SourceImage) (rbc : RBC) (frameThickness : float) (fontSize : float) (isTextBelow : bool) : RBCFrame =
 184         let frame = createRBCFrameFromExisting srcImg rbc (RBCFrame ()) frameThickness fontSize isTextBelow
 185         frame.SetValue (Panel.ZIndexProperty, Int32.MaxValue - rbc.num) // To be sure the
 186         frame.menuRBCSetAsHealthy.Click.AddHandler (fun obj args -> setAsInfected srcImg (frame.Tag :?> RBC) false)
 187         frame.menuRBCSetAsInfected.Click.AddHandler (fun obj args -> setAsInfected srcImg (frame.Tag :?> RBC) true)
 188         frame.ContextMenuOpening.AddHandler (
 189             fun obj args ->
 190                 if (frame.Tag :?> RBC).infected then
 191                     frame.menuRBCSetAsHealthy.Visibility <- Visibility.Visible
 192                     frame.menuRBCSetAsInfected.Visibility <- Visibility.Collapsed
 193                 else
 194                     frame.menuRBCSetAsHealthy.Visibility <- Visibility.Collapsed
 195                     frame.menuRBCSetAsInfected.Visibility <- Visibility.Visible
 196         )
 197         frame.ContextMenuClosing.AddHandler (fun obj args -> if not frame.IsMouseOver then highlightRBCFrame frame false )
 198         frame.MouseEnter.AddHandler (fun obj args -> highlightRBCFrame frame true)
 199         frame.MouseLeave.AddHandler (fun obj args -> if not frame.grid.ContextMenu.IsOpen then highlightRBCFrame frame false)
 200         frame
 201
 202     and updateRBCFramesPreview () =
 203         match state.CurrentImage with
 204         | Some srcImg ->
 205             let mutable currentPreview = 0
 206             for rbc in srcImg.RBCs |> List.filter (fun rbc -> displayHealthy || rbc.infected) do
 207                 let previewInfected =
 208                     if currentPreview < win.stackRBC.Children.Count then
 209                         createRBCFrameFromExisting srcImg rbc (win.stackRBC.Children.[currentPreview] :?> RBCFrame) 1. 12. false
 210                     else
 211                         let f = createRBCFrame srcImg rbc 1. 12. false
 212                         f.MouseLeftButtonUp.AddHandler (fun obj args -> zoomToRBC (f.Tag :?> RBC))
 213                         win.stackRBC.Children.Add f |> ignore
 214                         f
 215
 216                 currentPreview <- currentPreview + 1
 217
 218                 previewInfected.Height <- win.stackRBC.ActualHeight
 219                 previewInfected.Width <- win.stackRBC.ActualHeight * rbc.size.Width / rbc.size.Height
 220                 previewInfected.border.Fill <- ImageBrush (BitmapSourceConvert.ToBitmapSource (extractRBCPreview srcImg.Img rbc))
 221
 222             win.stackRBC.Children.RemoveRange (currentPreview, win.stackRBC.Children.Count - currentPreview)
 223         | _ -> ()
 224
 225         updateViewportPreview ()
 226
 227     let updateRBCFramesCurrent () =
 228         match state.CurrentImage with
 229         | Some srcImg ->
 230             let mutable currentCanvas = 0
 231             let strokeThickness = frameStrokeThickness srcImg.AverageRBCSize
 232             let fontSize = frameFontSize srcImg.AverageRBCSize
 233             for rbc in srcImg.RBCs do
 234                 let frame =
 235                     if currentCanvas < win.canvasCurrentImage.Children.Count then
 236                         createRBCFrameFromExisting srcImg rbc (win.canvasCurrentImage.Children.[currentCanvas] :?> RBCFrame) strokeThickness fontSize true
 237                     else
 238                         let f = createRBCFrame srcImg rbc strokeThickness fontSize true
 239                         win.canvasCurrentImage.Children.Add f |> ignore
 240                         f
 241
 242                 currentCanvas <- currentCanvas + 1
 243
 244                 Canvas.SetLeft (frame, rbc.center.X - rbc.size.Width / 2.)
 245                 Canvas.SetTop (frame, rbc.center.Y - rbc.size.Height / 2.)
 246
 247             for i in currentCanvas .. win.canvasCurrentImage.Children.Count - 1 do
 248                 win.canvasCurrentImage.Children.[i].Visibility <- Visibility.Hidden
 249         | _ -> ()
 250
 251     let askDocumentPathToSave () : string option =
 252         let dialog = SaveFileDialog (AddExtension = true, DefaultExt = PiaZ.extension, Filter = PiaZ.filter)
 253
 254         if state.FilePath <> "" then
 255             dialog.FileName <- FileInfo(state.FilePath).Name
 256         elif state.PatientID <> "" then
 257             dialog.FileName <- state.PatientID + PiaZ.extension
 258
 259         let res = dialog.ShowDialog ()
 260         if res.HasValue && res.Value then
 261             Some dialog.FileName
 262         else
 263             None
 264
 265     let saveCurrentDocument () =
 266         try
 267             if state.FilePath = "" then
 268                 match askDocumentPathToSave () with
 269                 | Some filepath ->
 270                     state.FilePath <- filepath
 271                     state.Save ()
 272                 | _ -> ()
 273             else
 274                 state.Save ()
 275             updateDocumentStatus ()
 276             displayStatusMessage "Document saved"
 277         with
 278         | :? IOException as ex ->
 279             Log.Error "%O" ex
 280             MessageBox.Show (sprintf "The document cannot be save in \"%s\"" state.FilePath, "Error saving the document", MessageBoxButton.OK, MessageBoxImage.Error) |> ignore
 281
 282     let saveCurrentDocumentAsNewFile () =
 283         match askDocumentPathToSave () with
 284         | Some filepath ->
 285             state.FilePath <- filepath
 286             saveCurrentDocument ()
 287         | _ -> ()
 288
 289     // Ask the use to save the current document if neccessary.
 290     let askSaveCurrent () =
 291         if state.AlteredSinceLastSave then
 292             match MessageBox.Show ("Would you like to save the current document?", "Saving the current document", MessageBoxButton.YesNo, MessageBoxImage.Question) with
 293             | MessageBoxResult.Yes -> saveCurrentDocument ()
 294             | _ -> ()
 295
 296     let updateCurrentImage () =
 297         match state.CurrentImage with
 298         | Some srcImg ->
 299             win.imgLogos.Visibility <- Visibility.Collapsed
 300
 301             // Highlight the preview.
 302             win.stackPreviews.Children
 303             |> Seq.cast<ImageSourcePreview>
 304             |> Seq.iter (fun preview -> preview.border.BorderThickness <- Thickness (if preview.Tag = (srcImg :> Object) then 3. else 0.))
 305
 306             win.canvasCurrentImage.Height <- float srcImg.Img.Height
 307             win.canvasCurrentImage.Width <- float srcImg.Img.Width
 308             win.canvasCurrentImage.Background <- ImageBrush (BitmapSourceConvert.ToBitmapSource (srcImg.Img))
 309
 310             updateRBCFramesCurrent ()
 311             updateRBCFramesPreview ()
 312
 313         | None ->
 314             win.imgLogos.Visibility <- Visibility.Visible
 315
 316             win.stackRBC.Children.Clear ()
 317             win.canvasCurrentImage.Children.Clear ()
 318             win.canvasCurrentImage.Background <- canvasCurrentImageColor
 319
 320         updateCurrentImageInformation ()
 321
 322     let setCurrentImage (srcImg : SourceImage) =
 323         if state.CurrentImage.IsNone || state.CurrentImage.Value <> srcImg then
 324             state.CurrentImage <- Some srcImg
 325             updateCurrentImage ()
 326
 327     let addPreview (srcImg : SourceImage) =
 328         let imgCtrl = ImageSourcePreview (Margin = Thickness 3.)
 329
 330         imgCtrl.menuRemoveImage.Click.AddHandler (
 331             fun obj args ->
 332                 win.stackPreviews.Children.Remove (imgCtrl)
 333                 let srcImg = imgCtrl.Tag :?> SourceImage
 334                 let currentRemoved = Some srcImg = state.CurrentImage
 335                 state.RemoveSourceImage srcImg
 336                 if currentRemoved then
 337                     updateCurrentImage ()
 338
 339                 updateGlobalParasitemia ()
 340
 341                 // Update image numbers.
 342                 win.stackPreviews.Children |> Seq.cast<ImageSourcePreview> |> Seq.iter (fun imgPreview -> imgPreview.txtImageNumber.Text <- (imgPreview.Tag :?> SourceImage).RomanNum)
 343         )
 344
 345         imgCtrl.Tag <- srcImg
 346         imgCtrl.txtImageNumber.Text <- string srcImg.RomanNum
 347         let width = 200
 348         let height = srcImg.Img.Height * width / srcImg.Img.Width
 349         imgCtrl.imagePreview.Source <- BitmapSourceConvert.ToBitmapSource (srcImg.Img.Resize (width, height, Emgu.CV.CvEnum.Inter.Cubic))
 350         win.stackPreviews.Children.Add imgCtrl |> ignore
 351
 352         // Zoom to a mouse position into the control 'imgCtrl'.
 353         let zoomTo (mousePos : Point) =
 354             let canvasW = win.canvasCurrentImage.ActualWidth * currentScale
 355             let canvasH = win.canvasCurrentImage.ActualHeight * currentScale
 356             let centerX = (mousePos.X - imgCtrl.BorderThickness.Left) / (imgCtrl.ActualWidth - imgCtrl.BorderThickness.Left) * canvasW
 357             let centerY = (mousePos.Y - imgCtrl.BorderThickness.Top) / (imgCtrl.ActualHeight - imgCtrl.BorderThickness.Top) * canvasH
 358             win.scrollViewCurrentImage.ScrollToHorizontalOffset (centerX - win.scrollViewCurrentImage.ViewportWidth / 2. + win.borderCurrentImage.BorderThickness.Left)
 359             win.scrollViewCurrentImage.ScrollToVerticalOffset (centerY - win.scrollViewCurrentImage.ViewportHeight / 2. + win.borderCurrentImage.BorderThickness.Top)
 360
 361         imgCtrl.MouseLeftButtonDown.AddHandler (
 362             fun obj args ->
 363                 setCurrentImage (state.SourceImages |> Seq.find (fun srcImg -> (srcImg :> Object) = imgCtrl.Tag))
 364                 imgCtrl.UpdateLayout ()
 365                 zoomTo (args.GetPosition (imgCtrl))
 366                 imgCtrl.CaptureMouse () |> ignore
 367         )
 368
 369         imgCtrl.MouseMove.AddHandler (
 370             fun obj args ->
 371                 if imgCtrl.IsMouseCaptured then
 372                     zoomTo (args.GetPosition imgCtrl)
 373         )
 374
 375         imgCtrl.MouseLeftButtonUp.AddHandler (
 376             fun obj args ->
 377                 if imgCtrl.IsMouseCaptured then
 378                     imgCtrl.ReleaseMouseCapture ()
 379         )
 380
 381     let updatePreviews () =
 382         win.stackPreviews.Children.Clear ()
 383         for srcImg in state.SourceImages do
 384             addPreview srcImg
 385         updateCurrentImage ()
 386
 387     let updateGUI () =
 388         win.txtPatient.Text <- state.PatientID
 389         updatePreviews ()
 390         updateGlobalParasitemia ()
 391         updateDocumentStatus ()
 392
 393     let loadFile (filepath : string) =
 394         askSaveCurrent ()
 395         let previousFilePath = state.FilePath
 396         try
 397             state.FilePath <- filepath
 398             state.Load ()
 399             updateGUI ()
 400         with
 401         | :? IOException as ex ->
 402             Log.Error "%O" ex
 403             state.FilePath <- previousFilePath
 404             MessageBox.Show (sprintf "The document cannot be loaded from \"%s\"" filepath, "Error loading the document", MessageBoxButton.OK, MessageBoxImage.Error) |> ignore
 405
 406     let askLoadFile () =
 407         let dialog = OpenFileDialog (Filter = PiaZ.filter)
 408         let res = dialog.ShowDialog ()
 409         if res.HasValue && res.Value then
 410             loadFile dialog.FileName
 411
 412     let newFile () =
 413         askSaveCurrent ()
 414         state.Reset ()
 415         updateGUI ()
 416
 417     let exportResults () =
 418         let extension = ".txt"
 419         let dialog = SaveFileDialog (AddExtension = true, DefaultExt = extension)
 420
 421         if state.FilePath <> "" then
 422             dialog.FileName <- Path.GetFileNameWithoutExtension state.FilePath + extension
 423         elif state.PatientID <> "" then
 424             dialog.FileName <- state.PatientID + extension
 425
 426         let res = dialog.ShowDialog ()
 427         if res.HasValue && res.Value then
 428             try
 429                 Export.exportResults state dialog.FileName
 430             with
 431             | :? IOException as ex ->
 432                 Log.Error "%O" ex
 433                 MessageBox.Show (sprintf "The results cannot be exported in \"%s\"" state.FilePath, "Error exporting the files", MessageBoxButton.OK, MessageBoxImage.Error) |> ignore
 434
 435     let importImage () =
 436         let dialog = OpenFileDialog (Filter = "Image Files|*.png;*.jpg;*.tif;*.tiff", Multiselect = true)
 437         let res = dialog.ShowDialog ()
 438         if res.HasValue && res.Value then
 439             let noSourceImage = state.SourceImages.Count () = 0
 440
 441             for filename in dialog.FileNames do
 442                 try
 443                     let srcImg = state.AddSourceImage filename defaultConfig
 444                     addPreview srcImg
 445                 with
 446                 | _ as ex ->
 447                     Log.Error "%O" ex
 448                     MessageBox.Show (sprintf "Unable to read the image from \"%s\"" filename, "Error adding an image", MessageBoxButton.OK, MessageBoxImage.Error) |> ignore
 449
 450             updateGlobalParasitemia ()
 451
 452             if noSourceImage then
 453                 updateCurrentImage ()
 454
 455     let showAnalysisWindow () =
 456         if Analysis.showWindow win state then
 457             updateGlobalParasitemia ()
 458             updateCurrentImage ()
 459
 460     let setHighlightRBC (highlight : bool) =
 461         displayHealthy <- highlight
 462         updateRBCFramesPreview ()
 463         updateRBCFramesCurrent ()
 464
 465     win.txtPatient.TextChanged.AddHandler (fun obj args -> state.PatientID <- win.txtPatient.Text)
 466
 467     win.menuExit.Click.AddHandler (fun obj args -> win.Close ())
 468     win.menuSave.Click.AddHandler (fun obj args -> saveCurrentDocument ())
 469     win.menuSaveAs.Click.AddHandler (fun obj args -> saveCurrentDocumentAsNewFile ())
 470     win.menuOpen.Click.AddHandler (fun obj args -> askLoadFile ())
 471     win.menuNew.Click.AddHandler (fun obj args -> newFile ())
 472     win.menuExportResults.Click.AddHandler (fun obj args -> exportResults ())
 473
 474     win.menuAddSourceImage.Click.AddHandler (fun obj args -> importImage ())
 475
 476     win.menuAnalysis.SubmenuOpened.AddHandler (fun obj args -> win.menuStartAnalysis.IsEnabled <- state.SourceImages.Count () > 0)
 477
 478     win.menuStartAnalysis.Click.AddHandler (fun obj args -> showAnalysisWindow ())
 479
 480     win.menuHightlightRBC.Click.AddHandler (fun obj args -> setHighlightRBC win.menuHightlightRBC.IsChecked)
 481
 482     win.menuAbout.Click.AddHandler (fun obj args -> About.showWindow win)
 483
 484     win.menuCommandLineArguments.Click.AddHandler (fun obj args -> CommandLineArguments.showWindow win)
 485
 486     win.Closing.AddHandler (fun obj args -> askSaveCurrent ())
 487
 488     // Zoom on the current image.
 489     let adjustCurrentImageBorders (deltaX : float) (deltaY : float) =
 490         win.borderCurrentImage.BorderThickness <-
 491             Thickness (
 492                 (win.scrollViewCurrentImage.ViewportWidth + deltaX) / 2.,
 493                 (win.scrollViewCurrentImage.ViewportHeight + deltaY) / 2.,
 494                 (win.scrollViewCurrentImage.ViewportWidth + deltaX) / 2.,
 495                 (win.scrollViewCurrentImage.ViewportHeight + deltaY) / 2.
 496             )
 497
 498     win.canvasCurrentImage.SizeChanged.AddHandler (
 499         fun obj args ->
 500             let deltaX = args.NewSize.Width - args.PreviousSize.Width
 501             let deltaY = args.NewSize.Height - args.PreviousSize.Height
 502             if deltaX > 0.5 || deltaY > 0.5 then
 503                 adjustCurrentImageBorders 0.0 0.0
 504                 // Center the view at the center of the image initialy.
 505                 win.scrollViewCurrentImage.UpdateLayout ()
 506                 win.scrollViewCurrentImage.ScrollToHorizontalOffset (win.borderCurrentImage.ActualWidth / 2. - win.scrollViewCurrentImage.ViewportWidth / 2.)
 507                 win.scrollViewCurrentImage.ScrollToVerticalOffset (win.borderCurrentImage.ActualHeight / 2. - win.scrollViewCurrentImage.ViewportHeight / 2.)
 508     )
 509
 510     win.scrollViewCurrentImage.SizeChanged.AddHandler (
 511         fun obj args ->
 512             let deltaX = args.NewSize.Width - args.PreviousSize.Width
 513             let deltaY = args.NewSize.Height - args.PreviousSize.Height
 514             adjustCurrentImageBorders deltaX deltaY
 515             win.scrollViewCurrentImage.ScrollToHorizontalOffset (win.scrollViewCurrentImage.HorizontalOffset + deltaX / 8.)
 516             win.scrollViewCurrentImage.ScrollToVerticalOffset (win.scrollViewCurrentImage.VerticalOffset + deltaY / 8.)
 517     )
 518
 519     let mutable maxScale = 4.
 520     let mutable minScale = 0.25
 521     let currentImageScaleTransform = ScaleTransform ()
 522     win.canvasCurrentImage.LayoutTransform <- currentImageScaleTransform
 523     win.borderCurrentImage.PreviewMouseWheel.AddHandler (
 524         fun _obj args ->
 525             let scaleFactor = if args.Delta > 0 then 2.0 else 0.5
 526             if scaleFactor > 1. && currentScale < maxScale || scaleFactor < 1. && currentScale > minScale then
 527                 let previousScale = currentScale
 528                 currentScale <-
 529                     let newScale = currentScale * scaleFactor
 530                     if newScale > maxScale then maxScale elif newScale < minScale then minScale else newScale
 531                 let realScaleFactor = currentScale / previousScale
 532
 533                 let centerX = win.scrollViewCurrentImage.HorizontalOffset + win.scrollViewCurrentImage.ViewportWidth / 2. - win.borderCurrentImage.BorderThickness.Left
 534                 let centerY = win.scrollViewCurrentImage.VerticalOffset + win.scrollViewCurrentImage.ViewportHeight / 2. - win.borderCurrentImage.BorderThickness.Top
 535
 536                 currentImageScaleTransform.ScaleX <- currentScale
 537                 currentImageScaleTransform.ScaleY <- currentScale
 538
 539                 win.scrollViewCurrentImage.ScrollToHorizontalOffset (centerX * realScaleFactor - win.scrollViewCurrentImage.ViewportWidth / 2. + win.borderCurrentImage.BorderThickness.Left)
 540                 win.scrollViewCurrentImage.ScrollToVerticalOffset (centerY * realScaleFactor - win.scrollViewCurrentImage.ViewportHeight / 2. + win.borderCurrentImage.BorderThickness.Top)
 541
 542             args.Handled <- true
 543     )
 544
 545     // Pan on the current image.
 546     let mutable scrollStartPosition = Point (0., 0.)
 547     let mutable scrollStartOffsetX = 0.
 548     let mutable scrollStartOffsetY = 0.
 549     win.borderCurrentImage.PreviewMouseLeftButtonDown.AddHandler (
 550         fun _obj args ->
 551             scrollStartPosition <- args.GetPosition win.scrollViewCurrentImage
 552             scrollStartOffsetX <- win.scrollViewCurrentImage.HorizontalOffset
 553             scrollStartOffsetY <- win.scrollViewCurrentImage.VerticalOffset
 554             win.borderCurrentImage.Cursor <- Input.Cursors.ScrollAll
 555             win.borderCurrentImage.CaptureMouse () |> ignore
 556             args.Handled <- true
 557     )
 558
 559     win.borderCurrentImage.PreviewMouseMove.AddHandler (
 560         fun _obj args ->
 561             if win.borderCurrentImage.IsMouseCaptured then
 562                 let position = args.GetPosition win.scrollViewCurrentImage
 563                 let deltaX = scrollStartPosition.X - position.X
 564                 let deltaY = scrollStartPosition.Y - position.Y
 565                 win.scrollViewCurrentImage.ScrollToHorizontalOffset (deltaX + scrollStartOffsetX)
 566                 win.scrollViewCurrentImage.ScrollToVerticalOffset (deltaY + scrollStartOffsetY)
 567
 568                 args.Handled <- true
 569     )
 570
 571     win.borderCurrentImage.PreviewMouseLeftButtonUp.AddHandler (
 572         fun _obj args ->
 573             if win.borderCurrentImage.IsMouseCaptured then
 574                 win.borderCurrentImage.Cursor <- Input.Cursors.Arrow
 575                 win.borderCurrentImage.ReleaseMouseCapture ()
 576                 args.Handled <- true
 577     )
 578
 579     // Shortcuts.
 580     // Save.
 581     win.InputBindings.Add (
 582         Input.KeyBinding (
 583             ViewModule.FunCommand ((fun obj -> saveCurrentDocument ()), (fun obj -> true)),
 584             Input.KeyGesture (Input.Key.S, Input.ModifierKeys.Control)
 585         )
 586     ) |> ignore
 587
 588     // Save as.
 589     win.InputBindings.Add (
 590         Input.KeyBinding (
 591             ViewModule.FunCommand ((fun obj -> saveCurrentDocumentAsNewFile ()), (fun obj -> true)),
 592             Input.KeyGesture (Input.Key.S, Input.ModifierKeys.Control ||| Input.ModifierKeys.Shift)
 593         )
 594     ) |> ignore
 595
 596     // Open.
 597     win.InputBindings.Add (
 598         Input.KeyBinding (
 599             ViewModule.FunCommand ((fun obj -> askLoadFile ()), (fun obj -> true)),
 600             Input.KeyGesture (Input.Key.O, Input.ModifierKeys.Control)
 601         )
 602     ) |> ignore
 603
 604     // New file.
 605     win.InputBindings.Add (
 606         Input.KeyBinding (
 607             ViewModule.FunCommand ((fun obj -> newFile ()), (fun obj -> true)),
 608             Input.KeyGesture (Input.Key.N, Input.ModifierKeys.Control)
 609         )
 610     ) |> ignore
 611
 612     // Export results.
 613     win.InputBindings.Add (
 614         Input.KeyBinding (
 615             ViewModule.FunCommand ((fun obj -> exportResults ()), (fun obj -> true)),
 616             Input.KeyGesture (Input.Key.E, Input.ModifierKeys.Control)
 617         )
 618     ) |> ignore
 619
 620     // Import an image.
 621     win.InputBindings.Add (
 622         Input.KeyBinding (
 623             ViewModule.FunCommand ((fun obj -> importImage ()), (fun obj -> true)),
 624             Input.KeyGesture (Input.Key.A, Input.ModifierKeys.Control)
 625         )
 626     ) |> ignore
 627
 628     // Show analysis dialog.
 629     win.InputBindings.Add (
 630         Input.KeyBinding (
 631             ViewModule.FunCommand ((fun obj -> showAnalysisWindow ()), (fun obj -> state.SourceImages.Count () > 0)),
 632             Input.KeyGesture (Input.Key.Y, Input.ModifierKeys.Control)
 633         )
 634     ) |> ignore
 635
 636     // Toggle RBC highlight.
 637     win.InputBindings.Add (
 638         Input.KeyBinding (
 639             ViewModule.FunCommand (
 640                 (
 641                     fun obj ->
 642                         win.menuHightlightRBC.IsChecked <- not win.menuHightlightRBC.IsChecked
 643                         setHighlightRBC win.menuHightlightRBC.IsChecked
 644                 ),
 645                 (fun obj -> true)
 646             ),
 647             Input.KeyGesture (Input.Key.H, Input.ModifierKeys.Control)
 648         )
 649     ) |> ignore
 650
 651     // Viewport preview.
 652     win.scrollViewCurrentImage.ScrollChanged.AddHandler (fun obj args -> updateViewportPreview ())
 653
 654     updateDocumentStatus ()
 655     win.gridImageInformation.Visibility <- Visibility.Hidden
 656
 657     win.Show ()
 658
 659     match fileToOpen with
 660     | Some filepath -> loadFile filepath
 661     | None -> ()
 662
 663     app.Run ()